RT info:eu-repo/semantics/article
T1 Treatment of comorbid alcohol dependence and anxiety disorder: Review of the scientific evidence and recommendations for treatment
A1 Gimeno, Carmen
A1 Dorado, María Luisa
A1 Roncero, Carlos
A1 Szerman, Nestor
A1 Vega, Pablo
A1 Balanzá Martínez, Vicent
A1 Álvarez González, Francisco Javier
K1 Alcohol-use disorder
K1 Trastorno por consumo de alcohol
K1 Anxiety disorders
K1 Trastorno de ansiedad
K1 Comorbidity
K1 Comorbilidad
K1 Co-occurring disorders
K1 Trastornos concurrentes
AB Patients with alcohol-use disorders (AUDs) have a high prevalence of anxiety disorders (AnxDs). “Co-occurring disorders” refers to the coexistence of an AUD and/or drug related disorders with another non-addictive psychiatric disorder. The aim of this study was to assess the effectiveness of psychopharmacological treatments and psychotherapy in patients with AUD and AnxD and to propose recommendations for the treatment of patients with comorbid AnxDs and AUDs. Randomized clinical trials, meta-analyses, and clinical guidelines were retrieved from PubMed, Embase, and Cochrane databases. Paroxetine was found to be effective in social anxiety patients with alcohol dependence. Selective serotonin reuptake inhibitors (SSRIs), especially sertraline, showed effective results in posttraumatic stress disorder and in comorbid AnxD–AUD. However, SSRIs should be used with caution when patients are actively drinking because they may increase alcohol consumption. Buspirone, gabapentin, and pregabalin were found to be effective in comorbid AnxD–AUD. The treatment of dual AnxDs should start as early as possible. Since AUDs and AnxDs can reinforce each other, treatments targeting both pathologies can be effective. Women suffer from higher levels of stress and AnxDs than men, and they are also more vulnerable to maintaining alcohol consumption levels. Further research is needed in this comorbid patient population, including the study of different types of patients and gender perspectives.
PB Frontiers
SN 1664-0640
YR 2017
FD 2017
LK http://uvadoc.uva.es/handle/10324/45794
UL http://uvadoc.uva.es/handle/10324/45794
LA eng
NO Frontiers in Psychiatry, 2017, vol. 8. 14 p.
NO Producción Científica
DS UVaDOC
RD 07-ago-2024