RT info:eu-repo/semantics/article
T1 Trends in the prevalence and distribution of HTLV-1 and HTLV-2 infections in Spain
A1 Treviño, Ana
A1 Aguilera, Antonio
A1 Caballero, Estrella
A1 Benito, Rafael
A1 Parra, Patricia
A1 Eiros Bouza, José María
A1 Hernández, Araceli
A1 Calderón, Enrique
A1 Rodríguez, Manuel
A1 Torres, Álvaro
A1 García, Juan
A1 Ramos, José Manuel
A1 Roc, Lourdes
A1 Marcaida, Goitzane
A1 Rodríguez, Carmen
A1 Trigo, Matilde
A1 Gómez, César
A1 Ortiz de Lejarazu Leonardo, Raúl
A1 Mendoza, Carmen de
A1 Soriano, Vincent
K1 Seroprevalencia
K1 Epidemiología
K1 HTLV
K1 32 Ciencias Médicas
AB Background: Although most HTLV infections in Spain have been found in native intravenous drug users carrying HTLV-2, the large immigration flows from Latin America and Sub-Saharan Africa in recent years may have changed the prevalence and distribution of HTLV-1 and HTLV-2 infections, and hypothetically open the opportunity for introducing HTLV-3 or HTLV-4 in Spain. To assess the current seroprevalence of HTLV infection in Spain a national multicenter, cross-sectional, study was conducted in June 2009.Results: A total of 6,460 consecutive outpatients attending 16 hospitals were examined. Overall, 12% were immigrants, and their main origin was Latin America (4.9%), Africa (3.6%) and other European countries (2.8%). Nine individuals were seroreactive for HTLV antibodies (overall prevalence, 0.14%). Evidence of HTLV-1 infection was confirmed by Western blot in 4 subjects (prevalence 0.06%) while HTLV-2 infection was found in 5 (prevalence 0.08%). Infection with HTLV types 1, 2, 3 and 4 was discarded by Western blot and specific PCR assays in another two specimens initially reactive in the enzyme immunoassay. All but one HTLV-1 cases were Latin-Americans while all persons with HTLV-2 infection were native Spaniards.Conclusions:The overall prevalence of HTLV infections in Spain remains low, with no evidence of HTLV-3 or HTLV-4 infections so far.
PB BioMed Central (BMC)
SN 1743-422X
YR 2012
FD 2012
LK http://uvadoc.uva.es/handle/10324/46015
UL http://uvadoc.uva.es/handle/10324/46015
LA eng
NO Virology Journal, 2012, vol. 9, n. 1, art. 71
NO Producción Científica
DS UVaDOC
RD 21-dic-2024