RT info:eu-repo/semantics/article T1 Establishing laminin, collagen IV and chondroitin sulfate patterns in octocystogenesis A1 Callejo, Sagrario A1 Barbosa Cachorro, María Mercedes A1 Moro Balbás, José Antonio A1 Gato Casado, Ángel Luis A1 Alonso Revuelta, María Isabel A1 Barbosa Ayucar, Enrique K1 Embriología K1 Cáncer - Investigación AB The extracellular matrix has been sean to play a key role in many of the morphogenetic processes which take place during early ocular aniaga development. For soma time now it has been known that sulfatad proteoglycans are present ininitiallens development, as these molecules have been implied in morphogenetic processes such as lens invagination and induction (Webster et al., 1983, Peterson et al., 1995). The implication of sulfatad proteoglycans in these phenomena is attributed to their distribution pattern and their coinciding with a particular process, or to the changas found in this distribution patternin certain mutant strains of aphakic mica (Zwaan and Webster, 1984). Nevertheless, there is no direct evidence to support the implication of proteoglycans in the formation processes of the lens vesicle and its subsequent development. In this paper,we offer the preliminary results of an experimental study concerning selectiva disruption of sulfatad proteoglycans synthesis by means of a P-D Xyloside, and its effect on lens growth. PB Universidad de Valladolid. Facultad de Medicina SN 1547-6278 YR 1995 FD 1995 LK http://uvadoc.uva.es/handle/10324/4966 UL http://uvadoc.uva.es/handle/10324/4966 LA eng NO Organogénesis, p.249-250 NO Producción Científica DS UVaDOC RD 23-nov-2024