RT info:eu-repo/semantics/article T1 Improved corrosion behavior and biocompatibility of porous Titanium samples coated with bioactive Chitosan-based nanocomposites A1 García Cabezón, Ana Cristina A1 Godinho, Vanda A1 Salvo Comino, Coral A1 Torres Hernández, Yadir A1 Martín Pedrosa, Fernando K1 Titanium implants K1 Implantes de titanio K1 Electrodeposition K1 Electrodeposición K1 Chitosan-based nanocomposites K1 Nanocompuestos de quitosano AB Porous titanium implants can be a good solution to solve the stress shielding phenomenon. However, the presence of pores compromises mechanical and corrosion resistance. In this work, porous titanium samples obtained using a space-holder technique are coated with Chitosan, Chitosan/AgNPs and Chitosan/Hydroxyapatite using only one step and an economic electrodeposition method. The coatings’ topography, homogeneity and chemical composition were analyzed. A study of the effect of the porosity and type of coating on corrosion resistance and cellular behavior was carried out. The electrochemical studies reveal that porous samples show high current densities and an unstable oxide film; therefore, there is a need for surface treatments to improve corrosion resistance. The Chitosan coatings provide a significant improvement in the corrosion resistance, but the Chitosan/AgNPs and Chitosan/HA coatings showed the highest protection efficiency, especially for the more porous samples. Furthermore, these coatings have better adherence than the chitosan coatings, and the higher surface roughness obtained favors cell adhesion and proliferation. Finally, a combination of coating and porous substrate material with the best biomechanical balance and biofunctional behavior is proposed as a potential candidate for the replacement of small, damaged bone tissues. PB MDPI SN 1996-1944 YR 2021 FD 2021 LK https://uvadoc.uva.es/handle/10324/50952 UL https://uvadoc.uva.es/handle/10324/50952 LA eng NO Materials, 2021, vol. 14, n. 21, 6322 NO Producción Científica DS UVaDOC RD 23-nov-2024