RT info:eu-repo/semantics/article
T1 Course of vascular access and relationship with treatment of anemia
A1 Portolés Pérez, Jose Maria
A1 López Gómez, Juan Manuel
A1 Gruss Vergara, Enrique
A1 Aljama García, Pedro
K1 Diálisis
K1 Hemodiálisis
K1 Anemia
K1 Cateterismo
K1 3205.06 Nefrología
AB Background and objectives: Maintenance of the vascular access is a crucial factor in hemodialysis, but large studies of factors that are predictive of thrombosis are lacking. Design, setting, participants, & measurements: This prospective, multicenter study investigated a cohort to describe the management of vascular access and establish the influence of anemia as a risk factor. The cohort included 1710 patients (aged 64.4 yr; 60% men) who were followed every 3 mo at 119 centers during 12 mo. On inclusion, 9.6% had a catheter, 80.3% had a native arteriovenous fistula, and 10.1% had a polytetrafluoroethylene graft. Results: Low baseline hemoglobin increased the risk for vascular access events. The risk was higher with a polytetrafluoroethylene graft and a catheter versus arteriovenous fistula. The multivariate model included type of vascular access, previous cardiovascular events, and noncorrected anemia. The likelihood of remaining free of vascular access events 12 mo later was0.727 (baseline hemoglobin <10.0 g/dl), 0.801 (10.01 to 11.0 g/dl), 0.814 (11.01 to 12.0 g/dl), and 0.833 (>12.0 g/dl), figures similar to those obtained with hemoglobin from the trimester before the event. The Cox model included type of vascular access. Conclusions: Correcting anemia did not increase the risk for vascular access–related events, and anemia that was resistant to treatment identified a subgroup of patients with higher comorbidity and higher likelihood of a vascular access event.
PB American Society of Nephrology
SN 1555-9041
YR 2007
FD 2007
LK https://uvadoc.uva.es/handle/10324/50960
UL https://uvadoc.uva.es/handle/10324/50960
LA eng
NO Clinical Journal of the American Society of Nephrology, 2007, vol. 2,  n. 6, p.1163-1169
NO Producción Científica
DS UVaDOC
RD 07-jul-2024