RT info:eu-repo/semantics/article T1 Ectoine production from biogas in waste treatment facilities: A techno-economic and sensitivity analysis A1 Pérez Martínez, Víctor A1 Moltó, Jose Luis A1 Lebrero Fernández, Raquel A1 Muñoz Martínez, Raquel K1 Biogas valorization K1 Valorización de biogás K1 Ectoine K1 Ectoína K1 Sensitivity analysis K1 Análisis de sensibilidad AB The capacity of haloalkaliphilic methanotrophic bacteria to synthesize ectoine from CH4-biogas represents an opportunity for waste treatment plants to improve their economic revenues and align their processes to the incoming circular economy directives. A techno-economic and sensitivity analysis for the bioconversion of biogas into 10 t ectoine·y–1 was conducted in two stages: (I) bioconversion of CH4 into ectoine in a bubble column bioreactor and (II) ectoine purification via ion exchange chromatography. The techno-economic analysis showed high investment (4.2 M€) and operational costs (1.4 M€·y–1). However, the high margin between the ectoine market value (600–1000 €·kg–1) and the estimated ectoine production costs (214 €·kg–1) resulted in a high profitability for the process, with a net present value evaluated at 20 years (NPV20) of 33.6 M€. The cost sensitivity analysis conducted revealed a great influence of equipment and consumable costs on the ectoine production costs. In contrast to alternative biogas valorization into heat and electricity or into low added-value bioproducts, biogas bioconversion into ectoine exhibited high robustness toward changes in energy, water, transportation, and labor costs. The worst- and best-case scenarios evaluated showed ectoine break-even prices ranging from 158 to 275 €·kg–1, ∼3–6 times lower than the current industrial ectoine market value. PB ACS Publications SN 2168-0485 YR 2021 FD 2021 LK https://uvadoc.uva.es/handle/10324/51665 UL https://uvadoc.uva.es/handle/10324/51665 LA eng NO ACS Sustainable Chemistry & Engineering, 2021, vol. 9, n. 51. p. 17371-17380 NO Producción Científica DS UVaDOC RD 24-nov-2024