RT info:eu-repo/semantics/article
T1 Anisotropy measure from three diffusion-encoding gradient directions
A1 Aja Fernández, Santiago
A1 París l Bandrés, Guillem Lluis
A1 Martín Martín, Carmen
A1 Jones, Derek K.
A1 Tristán Vega, Antonio
K1 Anisotropy
K1 Anisotropía
K1 Brain
K1 Cerebro
AB We propose a method that can provide information about the anisotropy and orientation of diffusion in the brain from only 3 orthogonal gradient directions without imposing additional assumptions. The method is based on the Diffusion Anisotropy (DiA) that measures the distance from a diffusion signal to its isotropic equivalent. The original formulation based on a Spherical Harmonics basis allows to go down to only 3 orthogonal directions in order to estimate the measure. In addition, an alternative simplification and a color-coding representation are also proposed. Acquisitions from a publicly available database are used to test the viability of the proposal. The DiA succeeded in providing anisotropy information from the white matter using only 3 diffusion-encoding directions. The price to pay for such reduced acquisition is an increment in the variability of the data and a subestimation of the metric on those tracts not aligned with the acquired directions. Nevertheless, the calculation of anisotropy information from DMRI is feasible using fewer than 6 gradient directions by using DiA. The method is totally compatible with existing acquisition protocols, and it may provide complementary information about orientation in fast diffusion acquisitions.
PB Elsevier
SN 0730-725X
YR 2022
FD 2022
LK https://uvadoc.uva.es/handle/10324/52106
UL https://uvadoc.uva.es/handle/10324/52106
LA eng
NO Magnetic Resonance Imaging, 2022, vol. 88. p. 38-43
NO Producción Científica
DS UVaDOC
RD 27-abr-2024