RT info:eu-repo/semantics/article
T1 (Attenuated) hallucinations join basic symptoms in a transdiagnostic network cluster analysis
A1 Jimeno Bulnes, Natalia
A1 Gómez Pilar, Javier
A1 Poza Crespo, Jesús
A1 Hornero Sánchez, Roberto
A1 Vogeley, Kai
A1 Meisenzahl, Eva
A1 Lichtenstein, Theresa K.
A1 Rosen, Marlene
A1 Kambeitz, Joseph
A1 Klosterkötter, Joachim
A1 Schultze Lutter, Frauke
K1 Psychosis
K1 Psicosis
K1 Hallucinations
K1 Alucinaciones
K1 3211 Psiquiatría
AB Hallucinations are considered characteristic symptoms of psychosis and part of the ‘psychosis superspectrum’ of the Hierarchical Taxonomy Of Psychopathology (HiTOP) initiative. To gain insight into their psychopathological relevance, we studied their dimensional placement within a single dense transdiagnostic network constituting of basic symptoms as well as of attenuated and frank psychotic, and related symptoms. Newman's modularity analysis was used to detect symptom clusters in an earlier generated network (Jimeno, N., et al., 2020. Main symptomatic treatment targets in suspected and early psychosis: New insights from network analysis. Schizophr. Bull. 46, 884–895. https://doi.org/10.1093/schbul/sbz140). The constituting 86 symptoms were assessed with the Schizophrenia Proneness Instrument, Adult version (SPI-A), the Structured Interview for Psychosis-Risk Syndromes (SIPS), and the Positive And Negative Syndrome Scale (PANSS) in three adult samples of an early detection service: clinical high-risk (n = 203), first-episode psychosis (n = 153), and major depression (n = 104). Three clusters were detected: “subjective disturbances”, “positive symptoms and behaviors”, and “negative and anxious-depressive symptoms”. The predominately attenuated hallucinations of both SIPS and PANSS joined the basic symptoms in “subjective disturbances”, whereas other positive symptoms entered “positive symptoms and behaviors”. Our results underline the importance of insight in separating true psychotic hallucinations from other hallucinatory experiences that, albeit phenomenologically similar are still experienced with some insight, i.e., are present in an attenuated form. We conclude that, strictly, hallucinations held with any degree of insight should not be used to diagnose transition to or presence of frank psychoses and, relatedly, to justify antipsychotic medication.
PB Elsevier
SN 0920-9964
YR 2022
FD 2022
LK https://uvadoc.uva.es/handle/10324/52207
UL https://uvadoc.uva.es/handle/10324/52207
LA eng
NO Schizophrenia Research, 2022, vol. 243, p. 43-54
NO Producción Científica
DS UVaDOC
RD 26-abr-2024