RT info:eu-repo/semantics/article T1 In vitro antifungal activity of composites of AgNPs and polyphenol inclusion compounds against Fusarium culmorum in different dispersion media A1 Matei, Petruta Mihaela A1 Iacomi, Beatrice Michaela A1 Martín Gil, Jesús A1 Pérez Lebeña, Eduardo A1 Ramos Sánchez, María del Carmen A1 Barrio Arredondo, María Teresa A1 Martín Ramos, Pablo K1 Antifungal K1 Chitosan oligomers K1 Composites K1 Deep eutectic solvents K1 Phenolic compounds K1 Fusarium culmorum K1 Silver nanoparticles K1 31 Ciencias Agrarias AB Fusarium culmorum is a soil-borne fungus able to cause Fusarium head blight, one of the most important cereal diseases worldwide, which can result in significant yield losses of up to 50% and which jeopardizes food and feed safety due to the mycotoxins produced. In the study presented herein, the enhancement of the antifungal activity against this pathogen, resulting from the addition of silver nanoparticles (AgNPs) to different polyphenol-stevioside inclusion compounds, dispersed either in a chitosan oligomers hydroalcoholic solution or in a choline chloride:urea:glycerol deep eutectic solvent, was investigated in vitro. The polyphenols assayed were curcumin, ferulic acid, gallic acid and silymarin. Four composite concentrations (62.5, 125, 250 and 500 µg·mL−1), with and without AgNPs, were assessed, finding noticeable differences in mycelial growth inhibition, with EC50 and EC90 values ranging from 118 to 579 µg·mL−1 and from 333 to 2604 µg·mL−1, respectively. The obtained results evidenced the improved efficacy of the composites with AgNPs, a superior performance of the composites based on curcumin and ferulic acid, and the advantages of the deep eutectic solvent-based dispersion medium over the chitosan oligomers-based one. The reported composites hold promise for crop protection applications. PB MDPI SN 2073-4395 YR 2018 FD 2018 LK https://uvadoc.uva.es/handle/10324/52534 UL https://uvadoc.uva.es/handle/10324/52534 LA eng NO Agronomy, 2018, vol. 8, n. 11, p. 239 NO Producción Científica DS UVaDOC RD 07-ago-2024