RT info:eu-repo/semantics/article
T1 Intestinal fructose and glucose metabolism in health and disease
A1 Merino Antolín, Beatriz
A1 Fernández Díaz, Cristina María
A1 Cózar Castellano, Irene
A1 Perdomo Hernández, Germán
K1 Fructose
K1 Fructosa
K1 Glucose
K1 Glucosa
K1 Intestine
K1 Intestino
AB The worldwide epidemics of obesity and diabetes have been linked to increased sugar consumption in humans. Here, we review fructose and glucose metabolism, as well as potential molecular mechanisms by which excessive sugar consumption is associated to metabolic diseases and insulin resistance in humans. To this end, we focus on understanding molecular and cellular mechanisms of fructose and glucose transport and sensing in the intestine, the intracellular signaling effects of dietary sugar metabolism, and its impact on glucose homeostasis in health and disease. Finally, the peripheral and central effects of dietary sugars on the gut–brain axis will be reviewed.
PB MDPI
SN 2072-6643
YR 2020
FD 2020
LK https://uvadoc.uva.es/handle/10324/52814
UL https://uvadoc.uva.es/handle/10324/52814
LA eng
NO Nutrients, 2020, vol. 12, n. 1, 94
NO Producción Científica
DS UVaDOC
RD 26-abr-2024