RT info:eu-repo/semantics/article T1 On the probable composition of ‘Jamaican stone’ aphrodisiac A1 Martín Ramos, Pablo A1 Carrión Prieto, Paula A1 Silva Castro, Iosody A1 Ruiz Potosme, Norlan Miguel A1 Hernández Navarro, Salvador A1 Martín Gil, Jesús K1 Análisis espectral K1 Aphrodisiac cooking K1 Aphrodisiacs K1 Cocina afrodisiaca - Recetas K1 Afrodisiacos K1 Spectroscopy AB A dangerous aphrodisiac, commonly known as ‘Jamaican stone’, banned by the U.S. Food and DrugAdministration, has been studied by vibrational spectroscopy in order to solve the controversy on itscomposition. The results of the ATR-FTIR analysis revealed the presence of the a-pyrone ring, which ischaracteristic of bufadienolides from toad venom and bulbs of squill (Drimia maritima (L.) Stearn). Thisconclusion was reached after a comparative study with the spectra for phytochemicals derived fromgambir and cat’s claw, two Uncaria species also preconized as aphrodisiacs and deemed as possibleconstituents of the ‘stone’. Owing to their physiologic similarities to digoxin, bufadienolides have beenshown to produce a toxic profile similar to that of digoxin, although the lack one of the side chains foundon digoxin should allow the use of hemodialysis to treat ‘Jamaican stone’ overdose. PB Elsevier SN 1874-3900 YR 2017 FD 2017 LK https://uvadoc.uva.es/handle/10324/55979 UL https://uvadoc.uva.es/handle/10324/55979 LA eng NO Phytochemistry Letters, 2017, Vol. 19, págs. 30-33 NO Producción Científica DS UVaDOC RD 22-dic-2024