RT info:eu-repo/semantics/article
T1 The oxepane motif in marine drugs
A1 Barbero San Juan, Héctor
A1 Díez Poza, Carlos
A1 Barbero Pérez, María Asunción
K1 Marine drugs
K1 Oxepanes
K1 Total synthesi
K1 Biological activity
K1 23 Química
AB Oceans have shown to be a remarkable source of natural products. The biological properties of many of these compounds have helped to produce great advances in medicinal chemistry. Within them, marine natural products containing an oxepanyl ring are present in a great variety of algae, sponges, fungus and corals and show very important biological activities, many of them possessing remarkable cytotoxic properties against a wide range of cancer cell lines. Their rich chemical structures have attracted the attention of many researchers who have reported interesting synthetic approaches to these targets. This review covers the most prominent examples of these types of compounds, focusing the discussion on the isolation, structure determination, medicinal properties and total synthesis of these products.
PB MDPI
YR 2017
FD 2017
LK https://uvadoc.uva.es/handle/10324/57496
UL https://uvadoc.uva.es/handle/10324/57496
LA eng
NO Marine Drugs, 2017, vol. 15, n. 11, p. 361
NO Producción Científica
DS UVaDOC
RD 27-ene-2025