RT info:eu-repo/semantics/article
T1 A journey across dopamine Metabolism: A rotational study of DOPAC
A1 Sanz Novo, Miguel
A1 Kolesnikova, Lucie
A1 Insausti, Aran
A1 Alonso Hernández, José Luis
A1 León Ona, Iker
A1 Alonso Alonso, Elena Rita
K1 Neurotransmitters
K1 Epectroscopy
K1 Neurotrasnsmisores
K1 Espectroscopia de alta resolución
K1 Espectroscopia rotacional
K1 2206.07 Espectroscopia Molecular
AB DOPAC, a relevant scaffold in dopamine metabolism, was probed in the gas phase and interrogated by high-resolution rotational spectroscopy. Herein, three distinct conformers were isolated in a supersonic jet and identified for the first time through an examination of the trend of the rotational constants and the dipole moment selection rules. Additionally, we examined the plausible relaxation pathways of the low-energy conformers of DOPAC, which helped us to claim the indirect detection of two additional conformers, providing conclusive experimental evidence of the flexible nature of this biomolecule. The current investigation sheds some light on the differences between jet-cooled rotational experiments and matrix-isolation infrared spectroscopy.
PB Elsevier
SN 1386-1425
YR 2023
FD 2023
LK https://uvadoc.uva.es/handle/10324/58486
UL https://uvadoc.uva.es/handle/10324/58486
LA eng
NO Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy Volume 290, l 2023, 122303
NO Producción Científica
DS UVaDOC
RD 22-nov-2024