RT info:eu-repo/semantics/article
T1 Bone mineral density, bone remodeling and osteoprotegerin in patients with acute coronary syndrome
A1 Pérez Castrillon, José Luis
A1 Abad Manteca, Laura
A1 Vega, Gemma
A1 Sanz Cantalapiedra, Alberto
A1 San Miguel, Ángel
A1 Mazón Ramos, María de los Ángeles
A1 Luis Román, Daniel Antonio de
A1 Dueñas Laita, Antonio
K1 Osteoporosis
AB The objective of this study was to evaluate the relationship between coronary disease and osteoporosis and determine the effect ofosteoprotegerin (OPG) on bone remodeling and bone mineral density (BMD) in a group of patients with acute coronary syndrome. Eightythreepatients (52 males and 31 women) with acute coronary syndrome (75 patients with acute myocardial infarction and 8 with unstableangina) with an average age of 61±10 years were studied. Levels of osteocalcin, urinarydeoxypyridinoline, OPG and the receptor activator ofnuclear factor-κB ligand (RANKL) were determined during the hospital stay. Femoral neck, trochanter and lumbar spine densitometry wascarried out using a DXA densitometer. Thirty percent of patients presented osteoporosis (39% of females and 26% of males). Osteoporoticpatients were older and had a lower weight and height and elevated serum levels of osteocalcin (3.6±2.25 2.63 versus ±1.55, p=0.05).Levels of OPG and RANKL were similar in both groups and showed no relationship with BMD. In conclusion, no relationship was observedbetween the OPG/RANKL system and BMD in these patients.
PB Elsevier Ireland Ltd.
SN 0167-5273
YR 2008
FD 2008
LK http://uvadoc.uva.es/handle/10324/5881
UL http://uvadoc.uva.es/handle/10324/5881
LA eng
NO International Journal of Cardiology, 2008, vol. 129, p. 144-145
NO Producción Científica
DS UVaDOC
RD 24-nov-2024