RT info:eu-repo/semantics/article
T1 Relation of resistin levels with cardiovascular risk factors, insulin resistance and inflammation in naı¨ve diabetes obese patients
A1 Luis Román, Daniel Antonio de
A1 González Sagrado, Manuel
A1 Conde, R.
A1 Aller de la Fuente, Rocío
A1 Izaola Jauregui, Olatz
A1 Fuente, Beatriz de la
A1 Pérez Castrillon, José Luis
A1 Romero, E.
K1 Cardiovascular, Aparato - Enfermedades
K1 Diabetes
AB Background: The aim of the present study was to explore the relationship of resistin levelswith cardiovascular risk factors, insulin resistance and inflammation in naı¨ve diabeticpatients.Subjects: A population of 66 naı¨ve diabetic patients with obesity was analyzed. A completenutritional and biochemical evaluation was performed.Results: The mean age 56.9   11.6 years and the mean BMI was 37.8   6.3. Patients weredivided in two groups by median resistin value (3.3 ng/ml), group I (patients with the lowvalues, average value 2.5   0.5) and group II (patients with the high values, average value4.8   1.8). Patients in the group I had lower waist circumference, total cholesterol, LDLcholesteroland C-reactive protein than patients in group II. Correlation analysis showed asignificant correlation among resistin levels and the independent variables; BMI (r = 0.26;p < 0.05), waist circumference (r = 0.38; p < 0.05), fat mass (r = 0.28; p < 0.05), LDL-cholesterol(r = 0.3; p < 0.05), C-reactive protein (r = 0.28; p < 0.05). In the multivariate analysis, resistinconcentration increase 0.024 ng/ml (CI 95%: 0.006–0.42) for each mg/dl of C-reactive protein.Conclusion: Circulating resistins are associated with C-reactive protein in an independentway in naı¨ve diabetic patients.
PB Elsevier
SN 0168-8227
YR 2010
FD 2010
LK http://uvadoc.uva.es/handle/10324/5882
UL http://uvadoc.uva.es/handle/10324/5882
LA eng
NO Diabetes Research and Clinical Practice, 2010, vol. 89, p. 110-114
NO Producción Científica
DS UVaDOC
RD 30-jun-2024