RT info:eu-repo/semantics/article T1 Antioxidant supplementation modulates neutrophil inflammatory response to exercise-induced stress A1 Carrera Quintanar, Lucrecia A1 Funes Gómez, Lorena A1 Herranz López, María A1 Martínez Peinado, Pascual A1 Pascual García, Sandra A1 Sempere Ortells, Jose Miguel A1 Boix Castejón, Marina A1 Córdova Martínez, Alfredo A1 Pons Biescas, Antoni A1 Micol Molina, Vicente A1 Roche Collado, Enrique K1 Antioxidantes K1 Inflammation K1 Neutrophils K1 Oxidative stress K1 Polyphenols K1 2302 Bioquímica K1 2302.21 Biología Molecular AB The aim of the present report was to evaluate the inflammatory response to a 2000-m running test considering neutrophil myeloperoxidase as an inflammatory marker, and to verify if supplements rich in antioxidants could modulate Post-test antioxidant and anti-inflammatory responses. To this end, a 21-day homogenization period was carried out with three groups: a control group, a supplemented group taking an almond beverage enriched with vitamins C and E and a third group consuming the same beverage but enriched with Lippia citriodora extract. At the end of this period, participants performed a 2000-m run, and blood samples were obtained the day before and immediately after the running test. Plasma and neutrophils were isolated. As a result, plasma creatine kinase and myoglobin increased, indicating Post-test muscle damage. Plasma oxidative markers were increased in all groups, except in the group supplemented with the almond beverage. Neutrophil antioxidant enzymes were significantly increased only in the control group, suggesting an antioxidant effect of the supplements provided in the other groups. Myeloperoxidase activity was significantly increased after the test in the control group, while increased enzyme levels were detected in plasma of the supplement groups. Therefore, antioxidant consumption seems to favour myeloperoxidase release. The connection of this observation with post-exercise recovery will require further investigation. PB MDPI SN 2076-3921 YR 2020 FD 2020 LK https://uvadoc.uva.es/handle/10324/58846 UL https://uvadoc.uva.es/handle/10324/58846 LA eng NO Antioxidants, 2020, Vol. 9, Nº. 12, 1242 NO Producción Científica DS UVaDOC RD 24-nov-2024