RT info:eu-repo/semantics/article
T1 Electropolymerized polypyrrole silver nanocomposite coatings on porous Ti substrates with enhanced corrosion and antibacterial behavior for biomedical applications
A1 García Cabezón, Ana Cristina
A1 Godinho, Vanda
A1 Pérez González, Clara
A1 Torres de la Sierra, Yuri
A1 Martín Pedrosa, Fernando
K1 Nanotechnology
K1 Biomedical engineering
K1 Porous titanium
K1 Biocompatibility
K1 PPy-Ag composite coating
K1 Corrosion behaviour
K1 Titanio poroso
K1 Biocompatibilidad
K1 Revestimiento compuesto PPy-Ag
K1 Comportamiento a la corrosión
K1 3310.05 Ingeniería de Procesos
K1 3315.11 Pulvimetalurgia
AB This work proposes an innovative strategy that combines two well-known easy and economical preparation techniques: powder metallurgy based space-holder (SH) technique to provide porous biocompatible Ti substrates with balanced biomechanical behavior (for cortical bone tissue substitution) promoting bone ingrowth and biocoating infiltration, and electropolymerization to coat these substrates with the polypyrrole–silver nanoparticles (PPy-AgNPs) composite conductive polymers improving its corrosion resistance, biocompatibility with enhanced antibacterial activity. The deposited PPy-based coatings present a cauliflower-like structure well adhered to the porous substrates. The macroporosity of and rough inner pore surface of Ti SH substrates are responsible for the superior adhesion of the conductive polymer comparing to typical denser substrates obtained by powder metallurgy or forging. The corrosion protection properties of the coatings were investigated by open circuit potential and Anodic Polarization in PBS media to simulate possible implant conditions, revealing improved corrosion resistance for the composite coatings. The bioactivity of the coatings was evaluated by immersion tests, revealing the formation of Hydroxyapatite after 90-day immersion in PBS. In both PPy and PPy-AgNPs composite coatings, a displacement of the polarization curves to more noble potentials and a decrease in the current density, indicated that the coating's protective character is maintained after 90-day immersion in PBS. The antibacterial activity was assessed by using the Kirby–Bauer disk-diffusion method against Staphylococcus aureus (ATCC 25923). The inhibition halo increased from 5.5 ± 0.4 mm for the bare substrate to 8.2 ± 0.6 mm for the PPy-coated substrate and to 12.5 ± 0.7 mm for the PPy-AgNPs-coated porous Ti. This feature associated to the improved corrosion protection and biocompatibility would significantly contribute to the success of the potential use of porous Ti implants by SH technique envisaging substitution of small damaged bone tissues for example in tumors.
PB Elsevier
SN 2468-5194
YR 2023
FD 2023
LK https://uvadoc.uva.es/handle/10324/59073
UL https://uvadoc.uva.es/handle/10324/59073
LA eng
NO Materials Today Chemistry, 2023, vol. 29, 101433
NO Producción Científica
DS UVaDOC
RD 22-nov-2024