RT info:eu-repo/semantics/article T1 Effects of vitamin D in post-exercise muscle recovery. A systematic review and meta-analysis A1 Bello Gutierrez, Hugo José A1 Caballero García, Alberto A1 Pérez Valdecantos, Daniel A1 Roche Collado, Enrique A1 Noriega González, David César A1 Córdova Martínez, Alfredo K1 Creatine kinase K1 Ejercicio K1 Ejercicio físico K1 Vitamin D K1 Systematic reviews (Medical research) K1 Meta-analysis K1 Muscle damage K1 Myoglobin K1 Recovery AB Vitamin D is a key micronutrient modulating function and health in skeletal muscle. Therefore, we sought to systematically review the role of vitamin D in muscle recovery. A search in different databases (PubMed/MEDLINE, WOS, Google Scholar, and Scopus) was carried out following PRISMA® and PICOS. The search period was from inception to April 2020. Changes in post-exercise muscle damage were quantified comparing experimental group vs. placebo in each study by using number of participants, standardized mean difference (SMD), and standard error of the SMD. Hedges’s g was used to calculate the SMDs for each study group and biased by the inverse of variance that allows calculating an overall effect and the 95% confidence interval (CI). The net vitamin D supplementation effect was calculated by subtracting the placebo SMD from SMD of the experimental group. The DerSimonian and Laird method was used as a random effect model, taking into account that the effect of vitamin D on muscular damage may vary according to the dose administered and additional moderators. Six studies were selected. In conclusion, regarding circulating levels of muscle biomarkers and additional limitations of the studies, it cannot be concluded that vitamin D supplementation exerts an effect in post-exercise muscle recovery. Likely, the anti-inflammatory action of vitamin D is quicker than the recovery of tissue structure and function. This aspect is pending verification in future research. PB MDPI SN 2072-6643 YR 2021 FD 2021 LK https://uvadoc.uva.es/handle/10324/59080 UL https://uvadoc.uva.es/handle/10324/59080 LA eng NO Nutrients, 2021, Vol. 13, Nº. 11, 4013 NO Producción Científica DS UVaDOC RD 07-ago-2024