RT info:eu-repo/semantics/article
T1 A population-based registry analysis on hospitalized COVID-19 patients with previous cardiovascular disease: Clinical profile, treatment, and predictors of death
A1 Gutiérrez Abejón, Eduardo
A1 Herrera Gómez, Francisco Magno
A1 Martín García, Débora
A1 Tamayo Gómez, Eduardo
A1 Álvarez González, Francisco Javier
K1 COVID-19 (Disease)
K1 COVID-19
K1 Cardiovascular system - Diseases - Treatment
K1 Cerebrovascular disease
K1 Cardiology
K1 Heart failure
K1 Mortality
K1 2420 Virología
K1 3207.04 Patología Cardiovascular
AB A high percentage of patients with COVID-19 (coronavirus disease 2019) have previous cardiovascular disease (CVD). The findings presented here came from an epidemiological population-based registry study (real-world data) that enrolled all in-hospital COVID-19 patients with previous CVD from 1 March to 31 May 2020. Death, other comorbidities, hospital stay variables, ventilation type, and main clinical outcomes were evaluated. In Castile and Leon, 35.83% of the 7307 in-hospital COVID-19 patients who participated in this study had previous CVD, particularly arrhythmias (48.97%), cerebrovascular disease (25.02%), ischemic heart disease (22.8%), and chronic heart failure (20.82%). Of the patients, 21.36% were men and more than 90% were over 65 years of age, and the mortality rate achieved 32.93%. The most used medicines were antibiotics (91.41%), antimalarials (73.3%), steroids (46.64%), and antivirals (43.16%). The main predictors of death were age over 65 years (OR: 5), ventilation needs (OR: 2.81), treatment with anti-SIRS (systemic inflammatory response syndrome) medicines (OR: 1.97), antivirals (OR: 1.74) or steroids (OR: 1.68), SIRS (OR: 5.75), SARS (severe acute respiratory syndrome) (OR: 2.44), or AKI (acute kidney injury) (OR: 1.63) occurrence. Chronic heart failure and cerebrovascular disease were associated with a worse clinical course of COVID-19, especially in men older than 65 years with diabetes who developed SIRS, SARS, or AKI.
PB MDPI
SN 2308-3425
YR 2021
FD 2021
LK https://uvadoc.uva.es/handle/10324/59149
UL https://uvadoc.uva.es/handle/10324/59149
LA eng
NO Journal of Cardiovascular Development and Disease, 2021, Vol. 8, Nº. 12, 167
NO Producción Científica
DS UVaDOC
RD 04-dic-2024