RT info:eu-repo/semantics/article
T1 The immunomodulatory function of vitamin D, with particular reference to SARS-CoV-2
A1 Caballero García, Alberto
A1 Noriega González, David César
A1 Bello Gutierrez, Hugo José
A1 Roche Collado, Enrique
A1 Córdova Martínez, Alfredo
K1 COVID-19 (Disease)
K1 Vaccination
K1 Vacunación
K1 Vitamin D
K1 Immunomodulation
K1 2412 Inmunología
K1 2420 Virología
AB Vaccines are the only way to reduce the morbidity associated to SARS-CoV-2 infection. The appearance of new mutations urges us to increase the effectiveness of vaccines as a complementary alternative. In this context, the use of adjuvant strategies has improved the effectiveness of different vaccines against virus infections such as dengue, influenza, and common cold. Recent reports on patients infected by COVID-19 reveal that low levels of circulating vitamin D correlate with a severe respiratory insufficiency. The immunomodulatory activity of this micronutrient attenuates the synthesis of pro-inflammatory cytokines and at the same time, increases antibody production. Therefore, the present review proposes the use of vitamin D as adjuvant micronutrient to increase the efficacy of vaccines against SARS-CoV-2 infection.
PB MDPI
SN 1648-9144
YR 2021
FD 2021
LK https://uvadoc.uva.es/handle/10324/59168
UL https://uvadoc.uva.es/handle/10324/59168
LA eng
NO Medicina, 2021, Vol. 57, Nº. 12, 1321
NO Producción Científica
DS UVaDOC
RD 27-dic-2024