RT info:eu-repo/semantics/article T1 The influence of diet and probiotics on the response of solid tumours to immunotherapy: Present and future perspectives A1 Olivares Hernández, Alejandro A1 Figuero Pérez, Luis A1 González Sarmiento, Rogelio A1 León Jiménez, David A1 Cruz Hernández, Juan Jesús A1 Miramontes González, José Pablo K1 Cancer Research K1 Immunology K1 Medicina Interna K1 Oncología K1 Diet K1 Probiotics K1 Immunotherapy K1 Solid tumours K1 Dieta K1 Probióticos K1 Inmunoterapia K1 Tumores sólidos K1 3205 Medicina Interna K1 3201.01 Oncología AB Currently, various immunotherapeutic treatments are revolutionizing therapies that treat solid neoplasms. For these treatments, within immunotherapy, immune checkpoint inhibitors (ICIs) are the most widely used drugs. Diverse studies have shown the influence of diet and probiotics on the response to ICIs and consequently on the survival rates associated with different neoplasms. The use of various antibiotics, probiotics, and prebiotics has been associated with changes in the gut microbiota, and this, in turn, with resistance to immunotherapy. Together with the above, a lower intake of red meat and greater consumption of a Mediterranean, vegetarian, or vegan diet have led to a new way of understanding the mechanisms of resistance to ICIs. Omega-3 and polyphenol supplements are also powerful regulators of the microbiome whose influence on the immune system. Therefore, this review covers the influence of diet and probiotics on the response to immunotherapy in patients who have solid tumours. PB MDPI YR 2021 FD 2021 LK https://uvadoc.uva.es/handle/10324/59224 UL https://uvadoc.uva.es/handle/10324/59224 LA eng NO Applied Sciences, 2021, vol. 11, n. 18, 8445 NO Producción Científica DS UVaDOC RD 02-dic-2024