RT info:eu-repo/semantics/article
T1 Association between vitamin D deficiency and heart failure in the elderly
A1 Ruiz de Temiño de la Peña, Ángela
A1 Gil, Judith
A1 Maceda Pérez Grueso, María Teresa
A1 González, Marta
A1 Pineda, Mónica
A1 Dueñas Laita, Antonio
A1 Pérez Castrillon, José Luis
K1 Osteoporosis
AB Vitamin D (25-OH-vitamin D) is a hormone which acts on thecalcium-phosphorus metabolism and also has extraskeletal effects.In the cardiovascular system, it regulates the renin-angiotensinaldosteronesystem (RAAS), inhibits vascular smooth muscle proliferation,and suppresses cardiac hypertrophy and hypercontractility [1].We assessed the relationship between vitamin D deficiencyand heart failure (HF) in an elderly population. We carried out aprospective case-control study in the Internal Medicine Department,Rio Hortega Hospital, Valladolid in 2010. Twenty-five patients werediagnosed with HF and 19 were institutionalized controls with nohistory of cardiovascular disease (CVD). The age of patients and controlgroup was similar (83±7 years vs. 85±8 years, pN0.05). The sexdistribution don't show differences. HF was diagnosed according toclinical and laboratory criteria (B-type natriuretic peptideN400 pg/mL).Vitamin D insufficiency was defined as levelsb20 ng/ml and deficiencyasb10 ng/ml. Two-dimensional echocardiography evaluated systolicand diastolic function, pulmonary artery systolic pressure (PASP), atrialfibrillation and valvular disease in the HF group.
PB Elsevier Ireland Ltd.
SN 0167-5273
YR 2011
FD 2011
LK http://uvadoc.uva.es/handle/10324/5945
UL http://uvadoc.uva.es/handle/10324/5945
LA eng
NO International Journal of Cardiology, 2011, p. 407-408
NO Producción Científica
DS UVaDOC
RD 24-nov-2024