RT info:eu-repo/semantics/article
T1 Relationship between the main components of the crystalline lens and the anterior chamber depth after cataract formation
A1 Díez Montero, Cecilia
A1 López de la Rosa, Alberto
A1 López Miguel, Alberto
A1 Maldonado López, Miguel José
K1 Lens thickness
K1 Anterior cortex
K1 Posterior cortex
K1 Nucleus thickness
K1 Axial length
K1 Anterior chamber depth
K1 Cataract
K1 32 Ciencias Médicas
K1 3201.09 Oftalmología
AB Purpose To assess the relationship between anterior chamber depth (ACD) and lens thickness (LT), as well as its three maincomponents (anterior and posterior cortex and nucleus thickness), in cataractous and non-cataractous eyes, depending onthe axial length (AxL).Methods Anterior and posterior cortex and nucleus thickness of the crystalline lens, ACD, and AxL were measured usingoptical low-coherence reflectometry in cataractous and non-cataractous eyes. They were also classified into hyperopia, emme-tropia, myopia, and high myopia, depending on AxL; thus, eight subgroups were created. A minimum sample size of 44 eyes(of 44 patients) for each group was recruited. Linear models were fitted for the whole sample and each AxL subgroup to assessif there were differences in the relationships between the crystalline lens variables and ACD, including age as a covariate.Results Three hundred seventy cataract patients (237 females, 133 males) and 250 non-cataract controls (180 females, 70males), aged 70.5 ± 9.4 and 41.9 ± 15.5 years, respectively, were recruited. The mean AxL, ACD, and LT for the cataractousand non-cataractous eyes were 23.90 ± 2.05, 24.11 ± 2.11, 2.64 ± 0.45, and 2.91 ± 0.49, 4.51 ± 0.38, 3.93 ± 0.44 mm, respec-tively. The inverse relationship of LT, anterior and posterior cortex, and nucleus thickness with ACD was not significantly(p ≥ 0.26) different between cataractous and non-cataractous eyes. Further subclassification of the sample depending onAxL showed that the inverse relationship between the posterior cortex and ACD was no longer significant (p > 0.05) for anynon-cataractous AxL group. LT, anterior and posterior cortex, and nucleus thickness was not significantly (p ≥ 0.43) differentbetween cataractous and non-cataractous eyes for the whole sample, and all AxL groups after adjusting for age.Conclusions The presence of cataracts does not modify the inverse relationship of the LT, anterior and posterior cortex, andnucleus with ACD. And this relationship does not seem to depend importantly on AxL. Besides, the possible differencesin LT, anterior and posterior cortex, and nucleus between cataractous and non-cataractous eyes may not be caused by lensopacification, but possibly by the progressive lens growth due to aging.
PB Springer
SN 0721-832X
YR 2023
FD 2023
LK https://uvadoc.uva.es/handle/10324/59450
UL https://uvadoc.uva.es/handle/10324/59450
LA eng
NO Graefe's Archive for Clinical and Experimental Ophthalmology, 2023.
NO Producción Científica
DS UVaDOC
RD 11-jul-2024