RT info:eu-repo/semantics/article T1 Positivity to cocaine and/or benzoylecgonine in confirmation analyses for on-road tests in Spain A1 Herrera Gómez, Francisco Magno A1 Gutiérrez Abejón, Eduardo A1 García Mingo, Mercedes A1 Álvarez González, Francisco Javier K1 Automobile driving K1 Automóviles - Conducción K1 Drunk driving - Spain K1 Cocaine - Toxicology K1 Saliva K1 Psychotropic drugs K1 Abuso de substancias K1 Drugs of abuse - Analysis K1 Pharmacology K1 Toxicology K1 3214 Toxicología K1 3209 Farmacología AB We are using real-life data in order to determine the prevalence of driving with the presence of cocaine and/or benzoylecgonine (BZE), their concentrations, and their use in combination with other drugs. This study assessed data on Spanish drivers with confirmed drug-positive results recorded by the Spanish National Traffic Agency from 2011–2016. Frequencies of positivity for cocaine and/or BZE and concentration of such substances were obtained. Comparisons and univariate and multivariate regression analyses were performed. Drivers who tested positive for cocaine and/or BZE accounted for 48.59% of the total positive results for drugs. In positive cases for both cocaine and BZE, other substances were detected in 81.74%: delta-9-tetrahydrocannabinol (THC) (68.19%), opioids (20.78%) and amphetamine-like substances (16.76%). In the multivariate logistic regression analysis, the frequency of cocaine and/or BZE positive cases decreased with age (OR:0.97) and were less likely among women (OR:0.63). Concentrations (ng/mL) of cocaine (249.30) and BZE (137.90) were higher when both substances were detected together than when detected alone. Positivity to cocaine represented an important proportion among Spanish drivers who tested positive for drugs, and polysubstance use was especially observed in more than 8 out of 10 positive cases for cocaine and/or BZE. PB MDPI SN 1660-4601 YR 2021 FD 2021 LK https://uvadoc.uva.es/handle/10324/59726 UL https://uvadoc.uva.es/handle/10324/59726 LA eng NO International Journal of Environmental Research and Public Health, 2021, Vol. 18, Nº. 10, 5371 NO Producción Científica DS UVaDOC RD 07-ago-2024