RT info:eu-repo/semantics/article T1 Impact of depression and anxiety on dimensions of health-related quality of life in subjects with Parkinson’s disease enrolled in an association of patients A1 Chuquilín Arista, Fany A1 Álvarez Avellón, Tania A1 Menéndez González, Manuel K1 Parkinson's disease K1 Parkinson, Enfermedad de K1 Neurology K1 Dépression K1 Depresión mental K1 Anxiety K1 Ansiedad K1 Quality of life K1 Calidad de vida K1 Salud mental K1 32 Ciencias Médicas K1 3205.07 Neurología AB Parkinson’s disease (PD) is a complex disorder characterized by a wide spectrum of symptoms. Depression and anxiety are common manifestations in PD and may be determinants of health-related quality of life (HRQoL). The objective of this study is to determine the association of depression and anxiety with the dimensions of HRQoL in subjects with PD enrolled in an association of patients. Ninety-five community-based patients with PD diagnosis at different disease stages were studied. HRQoL was assessed using the Parkinson’s Disease Questionnaire (PDQ-39); depression and anxiety were assessed using the Beck Depression Inventory (BDI-II) and the State-Trait Anxiety Inventory (STAI), respectively. Our results showed that depression and anxiety were negatively associated with HRQoL measured by PDSI. Higher motor dysfunction measured by Hoehn and Yahr (H&Y) staging was also associated with worse HRQoL. Depression was the most influential variable in the model. All PDQ-39 dimensions except social support and bodily discomfort were associated with depression. Anxiety was associated with the emotional well-being and bodily discomfort dimensions. These results suggest that physicians should pay attention to the presence of psychiatric symptoms and treat them appropriately. PB MDPI SN 2076-3425 YR 2021 FD 2021 LK https://uvadoc.uva.es/handle/10324/59795 UL https://uvadoc.uva.es/handle/10324/59795 LA eng NO Brain Sciences, 2021, Vol. 11, Nº. 6, 771 NO Producción Científica DS UVaDOC RD 11-jul-2024