RT info:eu-repo/semantics/article T1 Prognostic role of TAPSE to PASP ratio in patients undergoing MitraClip procedure A1 Trejo Velasco, Blanca A1 Estevez Loureiro, Rodrigo A1 Carrasco Chinchilla, Fernando A1 Fernández Vázque, Felipe A1 Arzamendi, Dabit A1 Pan, Manuel A1 Pascual, Isaac A1 Nombela Franco, Luis A1 Amat Santos, Ignacio Jesús A1 Freixa, Xavier A1 Hernández Antolín, Rosa Ana A1 Trillo Nouche, Ramiro A1 Andraka Ikazuriaga, Leire A1 López Mínguez, José R. A1 Sanmiguel Cervera, Dario A1 Sanchis, Juan A1 Diez Gil, José Luis A1 Ruiz Quevedo, Valeriano A1 Urbano Carrillo, Cristóbal A1 Becerra Muñoz, Víctor Manuel A1 Benito González, Tomás A1 Li, Chi Hion A1 Mesa, Dolores A1 Avanzas, Pablo A1 Armijo, Germán A1 Serrador Frutos, Ana María A1 Sanchis, Laura A1 Fernández-Golfín Lobán, Covadonga A1 Cid Álvarez, Belén A1 Hernández García, José María A1 Garrote Coloma, Carmen A1 Fernández Peregrina, Estefanía A1 Romero, Miguel A1 León Arguero, Víctor A1 Cruz González, Ignacio K1 Cardiac surgery K1 Cardiology K1 Corazón - Cirugía K1 Pulmonary hypertension K1 Hipertensión pulmonar K1 Echocardiography K1 Mitral valve - Diseases - Imaging K1 Heart valves - Diseases - diagnostic imaging K1 Heart - Diseases K1 Corazón - Enfermedades K1 3205.01 Cardiología K1 3207.04 Patología Cardiovascular AB Background: Transcatheter mitral valve repair (TMVR) is an effective therapy for high-risk patients with severe mitral regurgitation (MR) but heart failure (HF) readmissions and death remain substantial on mid-term follow-up. Recently, right ventricular (RV) to pulmonary arterial (PA) coupling has emerged as a relevant prognostic predictor in HF. In this study, we aimed to assess the prognostic value of tricuspid annular plane systolic excursion (TAPSE) to PA systolic pressure (PASP) ratio as a non-invasive measure of RV-to-PA coupling in patients undergoing TMVR with MitraClip (Abbott, CA, USA). Methods: Multicentre registry including 228 consecutive patients that underwent successful TMVR with MitraClip. The sample was divided in two groups according to TAPSE/PASP median value: 0.35. The primary combined endpoint encompassed HF readmissions and all-cause mortality. Results: Mean age was 72.5 ± 11.5 years and 154 (67.5%) patients were male. HF readmissions and all-cause mortality were more frequent in patients with TAPSE/PASP ≤ 0.35: Log-Rank 8.844, p = 0.003. On Cox regression, TAPSE/PASP emerged as a prognostic predictor of the primary combined endpoint, together with STS-Score. TAPSE/PASP was a better prognostic predictor than either TAPSE or PASP separately. Conclusions: TAPSE/PASP ratio appears as a novel prognostic predictor in patients undergoing MitraClip implantation that might improve risk stratification and candidate selection. SN 2077-0383 YR 2021 FD 2021 LK https://uvadoc.uva.es/handle/10324/59993 UL https://uvadoc.uva.es/handle/10324/59993 LA eng NO Journal of Clinical Medicine, 2021, Vol. 10, Nº. 5, 1006 NO Producción Científica DS UVaDOC RD 24-nov-2024