RT info:eu-repo/semantics/article
T1 The tetrahydrofuran motif in marine lipids and terpenes
A1 González Andrés, Paula
A1 Fernández Peña, Laura
A1 Díez Poza, Carlos
A1 Barbero Pérez, María Asunción
K1 Marine natural products
K1 Natural products
K1 Productos naturales
K1 Heterocyclic compounds
K1 Tetrahydrofuran
K1 Organic compounds - Synthesis
K1 Compuestos orgánicos - Síntesis
K1 Biological activity
K1 Terpenes
K1 Terpenos - Biosíntesis
K1 Lipids
K1 Lípidos
K1 Fatty acid
K1 Organic chemistry
K1 Drug development
K1 Medicamentos - Investigación
K1 Farmacology - Research
K1 2306 Química Orgánica
K1 2306.10 Compuestos Heterocíclicos
K1 3209 Farmacología
AB Heterocycles are particularly common moieties within marine natural products. Specifically, tetrahydrofuranyl rings are present in a variety of compounds which present complex structures and interesting biological activities. Focusing on terpenoids, a high number of tetrahydrofuran-containing metabolites have been isolated during the last decades. They show promising biological activities, making them potential leads for novel antibiotics, antikinetoplastid drugs, amoebicidal substances, or anticancer drugs. Thus, they have attracted the attention of the synthetics community and numerous approaches to their total syntheses have appeared. Here, we offer the reader an overview of marine-derived terpenoids and related compounds, their isolation, structure determination, and a special focus on their total syntheses and biological profiles.
PB MDPI
SN 1660-3397
YR 2022
FD 2022
LK https://uvadoc.uva.es/handle/10324/61596
UL https://uvadoc.uva.es/handle/10324/61596
LA eng
NO Marine Drugs, 2022, Vol. 20, Nº. 10, 642
NO Producción Científica
DS UVaDOC
RD 17-jul-2024