RT info:eu-repo/semantics/article
T1 Cerebral white matter connectivity in adolescent idiopathic scoliosis: A diffusion magnetic resonance imaging study
A1 Noriega González, David César
A1 Crespo Sanjuan, Jesús
A1 Ardura Aragón, Francísco
A1 Calabia del Campo, Juan
A1 Alberola López, Carlos
A1 Luis García, Rodrigo de
A1 Caballero García, Alberto
A1 Córdova Martínez, Alfredo
K1 Adolescent idiopathic scoliosis
K1 Scoliosis
K1 Escoliosis
K1 Adolescentes - Enfermedades
K1 Spine - Diseases - Treatment
K1 Columna vertebral - Anomalías - Tratamiento
K1 Magnetic resonance imaging
K1 Resonancia magnética
K1 Fractional anisotropy
K1 Connectomics
K1 Artificial intelligence
K1 Neurosciences
K1 Tractography
K1 Neurology
K1 32 Ciencias Médicas
K1 1203.04 Inteligencia Artificial
K1 2490 Neurociencias
K1 3205.07 Neurología
AB Adolescent idiopathic scoliosis (AIS) is characterized by the radiographic presence of a frontal plane curve, with a magnitude greater than 10° (Cobb technique). Diffusion MRI can be employed to assess the cerebral white matter. The aim of this study was to analyze, by means of MRI, the presence of any alteration in the connectivity of cerebral white matter in AIS patients. In this study, 22 patients with AIS participated. The imaging protocol consisted in T1 and diffusion-weighted acquisitions. Based on the information from one of the diffusion acquisitions, a whole brain tractography was performed with the MRtrix tool. Tractography is a method to deduce the trajectory of fiber bundles through the white matter based on the diffusion MRI data. By combining cortical segmentation with tractography, a connectivity matrix of size 84 × 84 was constructed using FA (fractional anisotropy), and the number of streamlines as connectomics metrics. The results obtained support the hypothesis that alterations in cerebral white matter connectivity in patients with adolescent idiopathic scoliosis (AIS) exist. We consider that the application of diffusion MRI, together with transcranial magnetic stimulation neurophysiologically, is useful to search the etiology of AIS.
PB MDPI
SN 2227-9067
YR 2022
FD 2022
LK https://uvadoc.uva.es/handle/10324/61916
UL https://uvadoc.uva.es/handle/10324/61916
LA eng
NO Children, 2022, Vol. 9, Nº. 7, 1023
NO Producción Científica
DS UVaDOC
RD 27-dic-2024