RT info:eu-repo/semantics/article
T1 Adequacy of an altitude fitness program (Living and Training) plus intermittent exposure to hypoxia for improving hematological biomarkers and sports performance of elite athletes: A single-blind randomized clinical trial
A1 Fernández Lázaro, Diego
A1 Mielgo Ayuso, Juan Francisco
A1 Santamaría Gómez, Gema
A1 Gutiérrez Abejón, Eduardo
A1 Domínguez Ortega, Carlos
A1 García Lázaro, Sandra María
A1 Seco Calvo, Jesús
K1 Hypoxia
K1 Hipoxia
K1 Athletes
K1 Deportistas profesionales
K1 Oxygen
K1 Oxígeno
K1 Blood biomarkers
K1 Blood - Circulation
K1 Circulación sanguínea
K1 Sports performance
K1 Entrenamiento (Deportes)
K1 Safety profile
K1 Altitude training
K1 Public health
K1 2411.06 Fisiología del Ejercicio
K1 3212 Salud Publica
AB Athletes incorporate altitude training programs into their conventional training to improve their performance. The purpose of this study was to determine the effects of an 8-week altitude training program that was supplemented with intermittent hypoxic training (IHE) on the blood biomarkers, sports performance, and safety profiles of elite athletes. In a single-blind randomized clinical trial that followed the CONSORT recommendations, 24 male athletes were randomized to an IHE group (HA, n = 12) or an intermittent normoxia group (NA, n = 12). The IHE consisted of 5-min cycles of hypoxia–normoxia with an FIO2 of between 10–13% for 90 min every day for 8 weeks. Hematological (red blood cells, hemoglobin, hematocrit, hematocrit, reticulated hemoglobin, reticulocytes, and erythropoietin), immunological (leukocytes, monocytes, and lymphocytes), and renal (urea, creatinine, glomerular filtrate, and total protein) biomarkers were assessed at the baseline (T1), day 28 (T2), and day 56 (T3). Sports performance was evaluated at T1 and T3 by measuring quadriceps strength and using three-time trials over the distances of 60, 400, and 1000 m on an athletics track. Statistically significant increases (p < 0.05) in erythropoietin, reticulocytes, hemoglobin, and reticulocyte hemoglobin were observed in the HA group at T3 with respect to T1 and the NA group. In addition, statistically significant improvements (p < 0.05) were achieved in all performance tests. No variations were observed in the immunological or renal biomarkers. The athletes who were living and training at 1065 m and were supplemented with IHE produced significant improvements in their hematological behavior and sports performance with optimal safety profiles.
PB MDPI
SN 1660-4601
YR 2022
FD 2022
LK https://uvadoc.uva.es/handle/10324/62006
UL https://uvadoc.uva.es/handle/10324/62006
LA eng
NO International Journal of Environmental Research and Public Health, 2022, Vol. 19, Nº. 15, 9095
NO Producción Científica
DS UVaDOC
RD 11-jul-2024