RT info:eu-repo/semantics/article T1 The tetrahydrofuran motif in polyketide marine drugs A1 Fernández Peña, Laura A1 Díez Poza, Carlos A1 González Andrés, Paula A1 Barbero Pérez, María Asunción K1 Marine natural products K1 Productos naturales K1 Heterocyclic compounds K1 Compuestos heterocíclicos K1 Tetrahydrofuran K1 Organic compounds - Synthesis K1 Compuestos orgánicos - Síntesis K1 Biological activity K1 Marine pharmacology K1 Natural products - Therapeutic use K1 Drugs K1 Medicamentos K1 2306 Química Orgánica K1 3209 Farmacología AB Oxygen heterocycles are units that are abundant in a great number of marine natural products. Among them, marine polyketides containing tetrahydrofuran rings have attracted great attention within the scientific community due to their challenging structures and promising biological activities. An overview of the most important marine tetrahydrofuran polyketides, with a focused discussion on their isolation, structure determination, approaches to their total synthesis, and biological studies is provided. PB MDPI SN 1660-3397 YR 2022 FD 2022 LK https://uvadoc.uva.es/handle/10324/62059 UL https://uvadoc.uva.es/handle/10324/62059 LA eng NO Marine Drugs, 2022, Vol. 20, Nº. 2, 120 NO Producción Científica DS UVaDOC RD 10-mar-2025