RT info:eu-repo/semantics/article
T1 Effects of antioxidants on pain perception in patients with fibromyalgia—A systematic review
A1 Fernández Araque, Ana María
A1 Verde Rello, Zoraida
A1 Torres Ortega, Clara María
A1 Sáinz Gil, María
A1 Velasco González, Verónica
A1 González Bernal, Jerónimo J.
A1 Mielgo Ayuso, Juan Francisco
K1 Antioxidants
K1 Antioxidantes
K1 Fibromyalgia
K1 Fibromialgia
K1 Pain
K1 Dolor
K1 Chronic pain
K1 Dolor crónico
K1 Diet
K1 Dieta
K1 Dietetics
K1 Dietética
K1 Nutritional supplements
K1 Supplementation
K1 Pharmacology
K1 Nutrition
K1 Systematic reviews (Medical research)
K1 Medicina - Investigación
K1 3209 Farmacología
K1 3206 Ciencias de la Nutrición
K1 32 Ciencias Médicas
AB In recent years, antioxidant supplements have become popular to counteract the effects of oxidative stress in fibromyalgia and one of its most distressing symptoms, pain. The aim of this systematic review was to summarize the effects of antioxidant supplementation on pain levels perceived by patients diagnosed with fibromyalgia. The words used respected the medical search terms related to our objective including antioxidants, fibromyalgia, pain, and supplementation. Seventeen relevant articles were identified within Medline (PubMed), Scopus, Web of Science (WOS), the Cochrane Database of Systematic Review, and the Cochrane Central Register of Controlled Trials. This review found that antioxidant supplementation is efficient in reducing pain in nine of the studies reviewed. Studies with a duration of supplementation of at least 6 weeks showed a benefit on pain perception in 80% of the patients included in these studies. The benefits shown by vitamins and coenzyme Q10 are remarkable. Further research is needed to identify the effects of other types of antioxidants, such as extra virgin olive oil and turmeric. More homogeneous interventions in terms of antioxidant doses administered and duration would allow the effects on pain to be addressed more comprehensively.
PB MDPI
SN 2077-0383
YR 2022
FD 2022
LK https://uvadoc.uva.es/handle/10324/62608
UL https://uvadoc.uva.es/handle/10324/62608
LA eng
NO Journal of Clinical Medicine, 2022, Vol. 11, Nº. 9, 2462
NO Producción Científica
DS UVaDOC
RD 05-ene-2025