RT info:eu-repo/semantics/article
T1 Nitric-oxide-inducing factors on vitamin D changes in older people susceptible to suffer from sarcopenia
A1 Córdova Martínez, Alfredo
A1 Caballero García, Alberto
A1 Noriega González, David César
A1 Bello Gutierrez, Hugo José
A1 Pons Biescas, Antoni
A1 Roche Collado, Enrique
K1 Arginine
K1 Vitamin D
K1 Vitamina D
K1 Calcium
K1 Calcio
K1 Magnesium
K1 Magnesio
K1 Nitrate
K1 Nitratos
K1 Older people
K1 Personas de edad
K1 Sarcopenia
K1 Musculoskeletal system - Diseases
K1 Locomotor, aparato - Enfermedades
K1 Geriatrics
K1 Public Health
K1 32 Ciencias Médicas
K1 3201.07 Geriatría
K1 3212 Salud Publica
AB Calcium and magnesium, together with vitamin D and the hormones testosterone and cortisol, are key elements in muscle function, to maintain physical fitness. This study aims to analyze if supplementation with NO precursors (L-arginine, L-citrulline and beetroot extract) modulates the circulating levels of calcium, magnesium, vitamin D and steroid hormones in elders. Sixty-one volunteers (65.1 years old, 164.6 cm of height and 71.2 kg of weight) susceptible to develop sarcopenia participated in a physical activity program for 6 weeks. Participants were divided into four groups: one placebo and three taking one of the indicated supplements. Physical capacity was assessed through the following tests: (a) distance covered in 6 min by walking (endurance indicator); (b) hand grip (upper-body strength indicator); (c) time to cover 4 m by walking (speed indicator); and (d) time to perform five full squats (lower-body strength indicator). We concluded that there is a disparity in the association of steroid hormones, vitamin D levels and physical fitness. However, a significant inverse correlation between speed and endurance indicators was observed. Higher circulating vitamin D levels were observed in the L-arginine- and beetroot-supplemented groups. In conclusion, vasodilators increase vitamin D circulating levels that, in the long term, could maintain mineral homeostasis, improving muscular function.
PB MDPI
SN 1660-4601
YR 2022
FD 2022
LK https://uvadoc.uva.es/handle/10324/62717
UL https://uvadoc.uva.es/handle/10324/62717
LA eng
NO International Journal of Environmental Research and Public Health, 2022, Vol. 19, Nº. 10, 5938
NO Producción Científica
DS UVaDOC
RD 11-jul-2024