RT info:eu-repo/semantics/doctoralThesis T1 Impacto de la esterilización del aire con un dispositivo emisor de radiaciones ultravioletas C, en los resultados clínicos de los pacientes sometidos a cirugía cardíaca. A1 Álvarez Fuente, Elisa A2 Universidad de Valladolid. Escuela de Doctorado K1 Higiene ambienta K1 Intensive care U K1 Unidad de cuidados I K1 Nosocomial infection K1 Infección nosocomial K1 Sterilization K1 Esterilización K1 32 Ciencias Médicas AB Background: Numerous studies have evaluated the use of ultraviolet-C devices for terminal disinfection in hospitals, however, to date there is little information about the device’s final impact on patients. We investigated the effect of an ultraviolet air sterilizer (UVAS) on the clinical outcomes of cardiac surgery patients.Materials and methods: This random, prospective and non-interventional study included 1097 adult patients undergoing elective cardiac surgery: 522 stayed in an ICU room with UVAS (Medixair® ) and575 patients ICU room without UVAS and were used as a control. The primary outcome measure was to evaluate the effect of a UVAS on the overall prevalence of nosocomial infections in postoperative cardiac patients in ICUs.Results: No significant differences in ventilator-associated pneumonia (4.6% vs. 5.0%, p = 0.77) and total infection (14.0% vs. 15.5%, p = 0.45) rates were detected in patients with and without the UVAS. The length of stay in the intensive care unit and at the hospital was similar in both groups, UVAS (4.6 (8.2) days and 18.3 (5.5) days) and without UVAS (4.6 (7.3) days and 19.2 (18.6) days). The 30-day in-hospital mortality rate was 5.3%, no significant differences between groups were observed (p = 0.053).Conclusion: Novel ultraviolet-C technology has not been shown to significantly reduce nosocomial infections or mortality rates in cardiac surgery patients. YR 2023 FD 2023 LK https://uvadoc.uva.es/handle/10324/63651 UL https://uvadoc.uva.es/handle/10324/63651 LA spa NO Escuela de Doctorado DS UVaDOC RD 20-jun-2024