RT info:eu-repo/semantics/doctoralThesis
T1 Estimación de densidad mineral ósea mediante estudio de tomografía computarizada con protocolo GSI. Correlación densitométrica.
A1 Labrador Hernández, Gregorio de Jesús
A2 Universidad de Valladolid. Escuela de Doctorado
K1 Osteoporosis
K1 Vertebral fracture
K1 Fractura vertebral
K1 CT GSI
K1 TAC GSI
K1 32 Ciencias Médicas
AB The idea of this research work has focused on proposing a solution to a problem that day by day increases its prevalence and affects both men and women without distinction of age. The risk of suffering a fracture is the main clinical result of osteoporosis. Vertebral fractures represent the hallmark of them, with a prevalence calculated between 35 and 50% in women over 50 years of age, so it is essential to identify an osteoporotic vertebral fracture, in order to offer immediate treatment and avoid complications that they range from incapacitating pain to death caused by spinal cord compression. 100% of the patients who presented with vertebral fracture (VF) to the emergency department of the Hospital Clínico Universitario de Valladolid, who reported low back pain or low back trauma, were studied from August 2020 to August 2021 with subsequent follow-up of one year after definitive treatment, either conservative or surgical, and using a validated frailty assessment tool, where 11 clinical parameters are explored. A test that is routinely performed on patients who suffer OVF was used, such as the CT scan using its GSI tool and that match the results obtained in the different tests that serve as a diagnostic complement in the identification and planning and treatment of OVF. We use pathomorphological criteria to define VF, allowing categorical establishment according to the mechanism of the lesion, in order to identify the degree of instability and assess the prognosis for cure and possible treatment. Through Binary Logistic Regression, it was possible to find a test that would allow the diagnosis of osteoporosis as DXA does. Using the C statistic (ROC curve) the theoretical cut-off point of the new TACGSI2Bwater Test was established. Sensitivity, specificity, and positive predictive values were calculated to estimate osteoporotic patients. With this test it was determined that the presence of water in the measured vertebra classifies patients with 75% certainty. It can be used as a diagnostic tool for this pathology in the future.
YR 2023
FD 2023
LK https://uvadoc.uva.es/handle/10324/63685
UL https://uvadoc.uva.es/handle/10324/63685
LA spa
NO Escuela de Doctorado
DS UVaDOC
RD 17-jul-2024