RT info:eu-repo/semantics/article
T1 Fast determination of neonicotinoid insecticides in beeswax by ultra-high performance liquid chromatography-tandem mass spectrometry using an enhanced matrix removal-lipid sorbent for clean-up
A1 Valverde Bastardo, Silvia
A1 Ares Sacristán, Ana María
A1 Bernal Yagüe, José Luis
A1 Nozal Nalda, María Jesús del
A1 Bernal del Nozal, José
K1 Beeswax; Core-shell column; Dispersive solid-phase extraction; EMR-lipid sorbent; Neonicotinoid insecticides; UHPLC-MS/MS
AB This study is concerned with the development of a simple, rapid analytical method for simultaneously determining seven neonicotinoid insecticides (dinotefuran, nitenpyram, thiamethoxam, clothianidin, imidacloprid, acetamiprid and thiacloprid) in beeswax, by means of ultra-high performance liquid chromatography coupled to a quadrupole-time-of-flight mass detector. An efficient sample treatment is proposed (with average analyte recoveries between 93% and 106%) involving solvent extraction with a methanol and ethyl acetate mixture (70:30, v/v), centrifugation, freezing with dry ice, a dispersive solid phase extraction (enhanced matrix removallipid) followed by evaporation. Chromatographic analysis (10.5 min) was performed on a core-shell technologybased column (Kinetex® EVO C18). The method was fully validated in terms of selectivity, ruggedness, limits of detection (LODs) and quantification (LOQs), matrix effect, linearity, uncertainty, trueness and precision. Low LOQs, ranging from 1.2 to 4.9 μg/kg, were obtained in all cases. Finally, the proposed methods were applied to neonicotinoid analysis of twenty one beeswax samples from different Spanish regions, only one of the pesticides (imidacloprid) being detected at low levels (< LOQ).
PB Elsevier
SN 0026-265X
YR 2018
FD 2018
LK https://uvadoc.uva.es/handle/10324/64386
UL https://uvadoc.uva.es/handle/10324/64386
LA eng
NO Microchemical Journal, Junio 2018, vol. 142. p. 70-77.
NO Producción Científica
DS UVaDOC
RD 27-dic-2024