RT info:eu-repo/semantics/article T1 Reliability and agreement of subjective and objective non‐invasive break‐up time measurements in contact lens wearers A1 Valencia Nieto, Laura A1 López de la Rosa, Alberto A1 González García, María Jesús A1 López Miguel, Alberto K1 Agreement K1 CA-800 K1 Contact lens K1 EasyTear® VIEW+ K1 Non-invasive break-up time K1 Repeatability K1 2209.15 Optometría AB PurposeTo assess the reliability and agreement of non-invasive break-up time (NIBUT) in symptomatic and asymptomatic contact lens (CL) wearers using automatic objective and conventional subjective techniques.MethodsIn this prospective cross-sectional study, soft CL wearers, classified into symptomatic and asymptomatic based on the Contact Lens Dry Eye Questionnaire-8, underwent NIBUT assessment with the CL in situ. The CA-800 Corneal Analyzer and the EasyTear® VIEW+ Tearscope were used for objective and subjective evaluation, respectively. The within-subject repeatability and intraclass correlation coefficient (ICC) were calculated. The agreement between the devices was compared using the Bland–Altman method.ResultsA total of 141 CL wearers (51 male and 90 female) with a mean age of 33.6 (SD = 12.2) years were included. The repeatability and ICC values obtained with the CA-800 device when measuring NIBUT were 5.4 s and 58.6% across the whole sample, 4.2 s and 48.8% for the asymptomatic group and 7.1 s and 68.4% for the symptomatic group. When using the subjective method (EasyTear®), the respective repeatability and ICC values were 7.3 s and 32.7% for the whole sample, 6.5 s and 30.4% for the asymptomatic group and 8.6 s and 35.9% for the symptomatic group. The CA-800 device provided significantly (p < 0.001) shorter NIBUT values compared with EasyTear® for the whole sample (3.3 [2.9] vs. 8.1 [3.4] s), the asymptomatic (3.3 [3.0] vs. 7.7 [3.6] s) and the symptomatic (3.8 [2.9] vs. 8.6 [3.0] s) groups.ConclusionObjective (CA-800) NIBUT assessment provides more reliable measurements than the conventional subjective technique using the EasyTear® device. However, CL practitioners should also be aware that the objective method indicates shorter NIBUT values. Symptomatic CL wearers may also need a higher number of NIBUT measurements to obtain reliable estimations. PB Wiley SN 0275-5408 YR 2023 FD 2023 LK https://uvadoc.uva.es/handle/10324/64600 UL https://uvadoc.uva.es/handle/10324/64600 LA eng NO Ophthalmic and Physiological Optics, 2023, vol. 44, n. 1, p. 124-130 NO Producción Científica DS UVaDOC RD 27-dic-2024