RT info:eu-repo/semantics/article
T1 COVID-19 in children with neuromuscular disorders
A1 Natera-de Benito, Daniel
A1 Aguilera-Albesa, Sergio
A1 Costa-Comellas, Laura
A1 García-Romero, Mar
A1 Miranda-Herrero, María Concepción
A1 Rúbies Olives, Júlia
A1 García-Campos, Óscar
A1 Martínez del Val, Elena
A1 Martinez Garcia, Maria Josefa
A1 Medina Martínez, Inmaculada
A1 Fernandez-Garcia, Miguel A.
A1 Pascual-Pascual, Samuel Ignacio
A1 Gómez-Andrés, David
A1 Nascimento, Andres
A1 Camacho, Ana
A1 Ortez, Carlos
A1 Madruga, Marcos
A1 Munell, Francina
A1 Martí, Itxaso
A1 Pitarch, Inmaculada
A1 Domingo Jiménez, Maria Rosario
A1 Iglesias Escalera, Gema
A1 Fernández Ramos, Joaquin
A1 Gómez Garcia-de la Banda, Marta
A1 Ghandour, Diana
A1 Grimalt, María Antonia
A1 Nogales, Gisela
A1 Alvarez Molinero, Mireia
AB Objective Children with neuromuscular disorders have been assumed to be a particularly vulnerable population since the beginning of COVID-19. Although this is a plausible hypothesis, there is no evidence that complications or mortality rates in neuromuscular patients are higher than in the general population. The aim of this study is to describe the clinical charac teristics and outcome of COVID-19 in children with neuromuscular disorders.Methods A registry of children with neuromuscular conditions and laboratory-confrmed-SARS-CoV-2 infection was set up by the Neuromuscular Working Group of the Spanish Pediatric Neurology Society (SENEP). Data to be collected were focused on the characteristics and baseline status of the neuromuscular condition and the course of COVID-19.Results Severe complications were not observed in our series of 29 children with neuromuscular disorders infected by SARS-CoV-2. Eighty-nine percent of patients were clinically categorized as asymptomatic or mild cases and 10% as moderate cases. Patients with a relatively more severe course of COVID-19 had SMA type 1 and were between 1 and 3 years.Conclusions The course of COVID-19 in children with neuromuscular disorders may not be as severe as expected. The protective role of young age seems to outweigh the risk factors that are common in neuromuscular patients, such as a decreased respiratory capacity or a weak cough. Further studies are needed to know if this finding can be generalized to children with other chronic diseases
PB Springer-Verlag
SN 0340-5354
YR 2021
FD 2021
LK https://uvadoc.uva.es/handle/10324/64717
UL https://uvadoc.uva.es/handle/10324/64717
LA spa
NO Journal of Neurology. 2021
DS UVaDOC
RD 11-jul-2024