RT info:eu-repo/semantics/article T1 Embryonic cerebrospinal fluid in brain development: neural progenitor control A1 Gato, Ángel A1 Alonso, Maia Isabel A1 Martín, Cristina A1 Carnicero, Estela A1 Moro, José Antonio A1 de la Mano, Aníbal A1 Fernández, José María F A1 Desmond, Mary E K1 Neurorregeneración K1 Embriología AB Due to the effort of several research teams across the world, today we have a solid base of knowledge on the liquid contained in the brain cavities, its composition, and biological roles. Although the cerebrospinal fluid (CSF) is among the most relevant parts of the central nervous system from the physiological point of view, it seems that it is not a permanent and stable entity because its composition and biological properties evolve across life. So, we can talk about different CSFs during the vertebrate life span. In this review, we focus on the CSF in an interesting period, early in vertebrate development before the formation of the choroid plexus. This specific entity is called “embryonic CSF.” Based on the structure of the compartment, CSF composition, origin and circulation, and its interaction with neuroepithelial precursor cells (the target cells) we can conclude that embryonic CSF is different from the CSF in later developmental stages and from the adult CSF. This article presents arguments that support the singularity of the embryonic CSF, mainly focusing on its influence on neural precursor behavior during development and in adult life PB Karger SN 1332-8166; 0353-9504 YR 2014 FD 2014 LK https://uvadoc.uva.es/handle/10324/65019 UL https://uvadoc.uva.es/handle/10324/65019 LA eng NO Gato A, Alonso MI, Martín C, Carnicero E, Moro JA, De la Mano A, Fernández JM, Lamus F, Desmond ME. Embryonic cerebrospinal fluid in brain development: neural progenitor control. Croat Med J. 2014 Aug 28;55(4):299-305. NO Producción Científica DS UVaDOC RD 28-nov-2024