RT info:eu-repo/semantics/article T1 Tool for filtering PubMed search results by sample size A1 Baladrón García, Carlos A1 Santos Lozano, Alejandro A1 Aguiar Pérez, Javier Manuel A1 Lucía, Alejandro A1 Martín Hernández, Juan K1 Text mining K1 Clinical trial K1 Knowledge discovery K1 Sample size K1 32 Ciencias Médicas K1 33 Ciencias Tecnológicas AB The most used search engine for scientific literature, PubMed, provides tools to filter results by several fields. When searching for reports on clinical trials, sample size can be among the most important factors to consider. However, PubMed does not currently provide any means of filtering search results by sample size. Such a filtering tool would be useful in a variety of situations, including meta-analyses or state-of-the-art analyses to support experimental therapies. In this work, a tool was developed to filter articles identified by PubMed based on their reported sample sizes. A search engine was designed to send queries to PubMed, retrieve results, and compute estimates of reported sample sizes using a combination of syntactical and machine learning methods. The sample size search tool is publicly available for download at http://ihealth.uemc.es. Its accuracy was assessed against a manually annotated database of 750 random clinical trials returned by PubMed. Results Validation tests show that the sample size search tool is able to accurately (1) estimate sample size for 70% of abstracts and (2) classify 85% of abstracts into sample size quartiles. The proposed tool was validated as useful for advanced PubMed searches of clinical trials when the user is interested in identifying trials of a given sample size. PB Oxford University Press SN 1067-5027 YR 2018 FD 2018 LK https://uvadoc.uva.es/handle/10324/65066 UL https://uvadoc.uva.es/handle/10324/65066 LA eng NO Journal of the American Medical Informatics Association, Febrero 2018, vol. 25, n. 7. p. 774-779. NO Producción Científica DS UVaDOC RD 23-nov-2024