RT info:eu-repo/semantics/book
T1 Advanced therapy medicinal products for eye diseases: Goals and challenges
A1 Diebold Luque, María Yolanda
A1 García Posadas, Laura
A1 López Paniagua, Marina
A1 De La Mata Sampedro, Ana
A1 Galindo, Sara
A1 Blázquez, Francisco
A1 Calonge, Margarita
A1 Nieto Miguel, Teresa
A1 Herreras Cantalapiedra, José María
A1 Coco Martín, Rosa María
A1 Pastor Idoate, Salvador
A1 Pastor Jimeno, José Carlos
A1 Bhattarchajee, Promita
A1 Ahearne, Mark
A1 Nagai, Noriaki
A1 Sakurai, Shunsuke
A1 Seiriki, Ryotaro
A1 Minami, Misa
A1 Yamaguchi, Mizuki
A1 Deguchi, Saori
A1 Harata, Eiji
A1 Ruíz Alonso, Sandra
A1 Villate Beitia, Ilia
A1 Lafuente Merchan, Markel
A1 Puras, Gustavo
A1 Saenz del Burgo, Laura
A1 Pedraz, Jose Luis
A1 Bosworth, Lucy A
A1 Doherty, Kyle G
A1 Hsuan, James D
A1 Cray, Samuel P
A1 D'Sa, Raechelle A
A1 Pineda Molina, Catalina
A1 Badylak, Stephen F
A1 Williams, Rachel L
A1 Mirazul Islam, Mohamed
A1 AbuSamra, Dina B
A1 Chivu, Alexandru
A1 Argüeso, Pablo
A1 Dohlman, Claes H
A1 Patra, Hirak K
A1 Chodosh, James
A1 González Andrades, Miguel
A1 Sánchez Porras, David
A1 Caro Magdaleno, Manuel
A1 González Gallardo, Carmen
A1 García García, Oscar Darío
A1 Garzón, Ingrid
A1 Carriel, Victor
A1 Campos, Fernando
A1 Alaminos, Miguel
A2 MDPI
K1 Oftalmología
K1 Advanced Therapy Medicinal Products (ATMPs)
K1 Ocular diseases
K1 Medicamentos de Terapia Avanzada (ATMP)
K1 Enfermedades oculares
K1 3201.09 Oftalmología
AB The concept of advanced therapy medicinal products (ATMPs) encompasses novel kinds of medicines for human use that are based on genes, cells or tissues. These intend to offer not only regeneration, but complete functional recovery of diseased tissues and organs using different strategies. Gene therapy, cell therapy and tissue engineering are the main areas in which promising advanced therapies are emerging. The eye is a very complex organ whose main structures, thecornea and the retina, play a pivotal role in maintaining normal vision, as severe alterations in these tissues can lead to blindness. Ocular tissues are starting to benefit from ATMPs by fighting against the enormous complexity and devastating potential of many ocular diseases. However, developments arising from this field of work face important challenges related to vectors to deliver drugs and genetic material to target tissues, suitable biomaterials to prepare cell scaffolds and cell stemness, among others—not to mention the complicated legislation around ATMPs, the complexity in production and quality control and the absence of standardized protocols. The purpose of this Special Issue is to serve as an overview of the current progress in the application of cell and gene therapies, as well as tissue engineering to restore functionality in diseased ocular structures, and the challenges they deal with in order to get to patients.
SN 978-3-0365-2610-2
YR 2021
FD 2021
LK https://uvadoc.uva.es/handle/10324/65344
UL https://uvadoc.uva.es/handle/10324/65344
LA eng
NO Diebold, Yolanda; García Posadas, Laura (eds.). Advanced Therapy Medicinal Products for Eye Diseases: Goals and Challenges. Colección: Pharmaceutics, vol. 13. MDPI, 2021, 224 p.
NO Producción Científica
DS UVaDOC
RD 26-jun-2024