RT info:eu-repo/semantics/article
T1 Supercritical CO2 encapsulation of bioactive molecules in carboxylate based MOFs
A1 Monteagudo Olivan, Rebeca
A1 Cocero Alonso, María José
A1 Coronas, Joaquin
A1 Rodríguez Rojo, Soraya
K1 MOF
K1 Encapsulation
K1 Supercritical CO2
K1 Caffeine
K1 Carvacrol
K1 Host-guest interactions
AB Caffeine and carvacrol were encapsulated using supercritical CO2 (sc-CO2) impregnation in MOFs, MIL-53(Al)and M g-MOF-74, at different contact times. High additive loadings were achieved, 32.1 and 34.3% for caffeine, and for carvacrol 34.4 and 30.1%, respectively. The sc-CO2 encapsulation was more effective compared to the typical liquid phase encapsulation in ethanol. In fact, the encapsulation in Mg-MOF-74 was only possible in sc-CO2, null loading was observed in the liquid ethanol phase process. The products required no purification and the excess of additives could be reused. In all the studied cases, the materials maintained their crystalline structure and MIL-53(Al) displayed its characteristic flexibility adapting its structure to the additives. The total release of caffeine an carvacrol from Mg-MOF-74 was produced after 5 h in distilled water, while in the case of MIL-53(Al) no release was observed for 10 days.
PB Elsevier Ltd.
YR 2019
FD 2019
LK https://uvadoc.uva.es/handle/10324/65544
UL https://uvadoc.uva.es/handle/10324/65544
LA eng
NO Journal of CO₂ Utilization 30 (2019) 38–47
NO Producción Científica
DS UVaDOC
RD 08-ago-2024