RT info:eu-repo/semantics/article
T1 Inflammatory process on knee osteoarthritis in cyclists
A1 Noriega González, David César
A1 Caballero García, Alberto
A1 Roche Collado, Enrique
A1 Álvarez Mon, Melchor
A1 Córdova Martínez, Alfredo
K1 Cartilage
K1 Cartílago
K1 Collagen
K1 Colágeno
K1 Cytokines
K1 Citoquinas
K1 Joints - Diseases
K1 Articulaciones - Enfermedades
K1 Cycling
K1 Ciclismo
K1 Knee - Diseases
K1 Rodilla - Enfermedades
K1 Osteoarthritis
K1 Artrosis
K1 2411.06 Fisiología del Ejercicio
K1 32 Ciencias Médicas
K1 3205.09 Reumatología
AB Osteoarthritis is a disorder affecting the joints and is characterized by cellular stress and degradation of the extracellular matrix cartilage. It begins with the presence of micro- and macro-lesions that fail to repair properly, which can be initiated by multiple factors: genetic, developmental, metabolic, and traumatic. In the case of the knee, osteoarthritis affects the tissues of the diarthrodial joint, manifested by morphological, biochemical, and biomechanical modifications of the cells and the extracellular matrix. All this leads to remodeling, fissuring, ulceration, and loss of articular cartilage, as well as sclerosis of the subchondral bone with the production of osteophytes and subchondral cysts. The symptomatology appears at different time points and is accompanied by pain, deformation, disability, and varying degrees of local inflammation. Repetitive concentric movements, such as while cycling, can produce the microtrauma that leads to osteoarthritis. Aggravation of the gradual lesion in the cartilage matrix can evolve to an irreversible injury. The objective of the present review is to explain the evolution of knee osteoarthritis in cyclists, to show the scarce research performed in this particular field and extract recommendations to propose future therapeutic strategies.
PB MDPI
SN 2077-0383
YR 2023
FD 2023
LK https://uvadoc.uva.es/handle/10324/65706
UL https://uvadoc.uva.es/handle/10324/65706
LA eng
NO Journal of Clinical Medicine, 2023, Vol. 12, Nº. 11, 3703
NO Producción Científica
DS UVaDOC
RD 17-jul-2024