RT info:eu-repo/semantics/article T1 Effect of nanoclays on the electrochemical performance of LbL catechol sensors A1 García Hernández, Celia A1 García Cabezón, Ana Cristina A1 Rodríguez Méndez, María Luz A1 Martín Pedrosa, Fernando K1 Electrochemistry K1 Química analítica K1 Halloysite nanotubes K1 Copper phthalocyanine K1 Polyethylenimine K1 Nanotubos de halloysita K1 Ftalocianina de cobre K1 Polietilenimina K1 23 Química AB Halloysite nanotubes (HNTs) are excellent candidates to improve the immobilization of electroactive materials or enzymes due to their tubular structure and properties. In this work, an improved LbL based catechol sensor has been developed using a combination of sensing materials with complementary activity. These include sulfonated copper phthalocyanine (CuPcSO3−) acting as electrocatalytic material, poly(ethyleneimine) (PEI) to increase the charge injection efficiency and the increase of the surface provided by HNTs. The LbL film has been used as the sensing platform to deposit tyrosinase in order to further enhance the performance of the developed sensor towards catechol. The LbL films were characterized by using UV–Vis, FTIR and cyclic voltammetry. The limits of detection, repeatability and reproducibility of the sensors and the biosensor were evaluated. The limits of detection were 1.23 μmol·L−1 for the optimized (PEI/CuPcSO3−) sensor, 0.987 μmol·L−1 for the (PEI/HNT/PEI/CuPcSO3−) sensor and 0.938 μmol·L−1 for the (PEI/HNT/PEI/CuPcSO3−)-Tyrosinase sensor. PB Elsevier SN 0013-4686 YR 2024 FD 2024 LK https://uvadoc.uva.es/handle/10324/65966 UL https://uvadoc.uva.es/handle/10324/65966 LA eng NO Electrochimica Acta Volume, 2024, vol. 476, 143717 NO Producción Científica DS UVaDOC RD 27-jul-2024