RT info:eu-repo/semantics/article
T1 Analysis of the functional EEG network in an Ecuadorian schizophrenia sample
A1 Rodríguez-Lorenzana, Alberto
A1 Torres-Tapia, Mabel
A1 Parra, Cesar
A1 Díez, Álvaro
A1 Arjona, Antonio
A1 Gomez-Pilar, Javier
A1 Pasquel, Erika
A1 Granizo, Diego
A1 Molina, Vicente
AB AbstractBackground and objectivesHigher mental functions depend on global functional coordination of the brain. Our aim was to study the baseline condition and modulation of functional networks in a previously unevaluated clinical population, compare the results with a population from another country, and analyze their relationship with cognitive functioning.MethodsWe evaluated the functioning of brain networks by EEG in 24 patients with schizophrenia and 32 healthy Ecuadorian controls. EEG recordings were made at rest and while performing a P300 task. Small world (SW), Path Length (PL), clustering coefficient (CLC) and connective strength (CS) values were calculated in both conditions. The values obtained were compared between groups, with the results of Spanish patients, and the relationship between the connective parameters and the cognitive performance of the participants was analyzed.ResultsHigher PL, CLC and CS values were identified in patients diagnosed with schizophrenia compared to controls (in basal condition) and lower SW values in this same condition. Ecuadorian patients obtained higher values than Spanish patients in the PL and CLC parameters and lower values for the SW parameter, despite these differences, the pattern of alteration in both samples followed the same trend. Finally, the alteration of CS, SW, CLC and PL parameters at baseline was related to cognitive performance.ConclusionThe connective alterations identified in Ecuadorian schizophrenic patients are consistent with those found in another sample with different genetic, environmental and cultural conditions. In addition, these alterations were associated with worse performance in different cognitive domains.
PB Elsevier
SN 0213-6163
YR 2021
FD 2021
LK https://uvadoc.uva.es/handle/10324/66443
UL https://uvadoc.uva.es/handle/10324/66443
LA spa
NO European Journal of Psychiatry 35(4), 216-224
DS UVaDOC
RD 24-nov-2024