RT info:eu-repo/semantics/article
T1 Gamma Power and Cognition in Patients with Schizophrenia and Their First-Degree Relatives
A1 Díez, Álvaro
A1 Suazo, Vanessa
A1 Casado, Pilar
A1 Martín-Loeches, Manuel
A1 Molina, Vicente
AB Background: Gamma oscillations are essential for functional neural assembly formation underlying higher cerebral functions. Previous studies concerning gamma band power in schizophrenia have yielded diverse results.Methods: In this study, we assessed gamma band power in minimally treated patients with schizophrenia, their first-degree relatives and healthy controls during an oddball paradigm performance, as well as the relation between gamma power and cognitive performance.Results: We found a higher gamma power in the patient group than in the healthy controls at the P3, P4, Fz, Pz and T5 sites. Compared with their relatives, gamma power in the patients was only marginally higher over P3 and P4. We found a nearly significant inverse association between gamma power at F4 and Tower of London performance in the patients, as well as a significant inverse association between gamma power at T5 and verbal memory and working memory scores in the relatives.Conclusion: These results support higher total gamma power in association with schizophrenia and its inverse association with cognitive performance in patients and their first-degree relatives.
SN 0302-282X
YR 2014
FD 2014
LK https://uvadoc.uva.es/handle/10324/66463
UL https://uvadoc.uva.es/handle/10324/66463
LA spa
NO Neuropsychobiology 69(2):120-8
DS UVaDOC
RD 24-nov-2024