RT info:eu-repo/semantics/article T1 Influence of keratoconus severity on detecting true progression with Scheimpflug imaging and anterior segment optical coherence tomography A1 Ortiz Toquero, Sara A1 Fuente García, Carlota A1 Auladell, Clara A1 Arnalich Montiel, Francisco K1 Keratoconus K1 Queratocono K1 Ophthalmology K1 Tomography K1 Tomografía K1 Reproducibility K1 Cornea - Diseases K1 Córnea - Enfermedades K1 Eye - Diseases - Treatment K1 Ojo - Enfermedades y defectos - Tratamiento K1 2209 Óptica K1 3201.09 Oftalmología AB To determine consistent change over time in keratoconus disease, it is necessary to establish progression cut-off values based on intersession variability of the device used to monitor the cornea. The aim of this study was to analyze the accuracy of corneal parameters using Scheimpflug tomography and anterior segment optical coherence tomography in healthy and keratoconic eyes of varying severity to determine the cut-off values that indicate real progression. Three repeated measurements of each cornea of healthy (20 eyes) and keratoconic eyes (mild = 16, moderate = 25 and severe = 20) were recorded using Pentacam and Casia SS-1000 devices, which were repeated 2–3 weeks later. K1, K2, maximal anterior and posterior keratometry, and corneal thickness at the thinnest location (TCT) were collected. The accuracy was excellent with both devices; however, the Casia device presented better repeatability and reproducibility in all parameters in all groups compared to the Pentacam. The cut-off of the Pentacam and Casia in the mild stage were lower (K1 = 0.50 and 0.37 D; K2 = 0.51 and 0.37 D; Kmax-A = 1.24 and 0.65 D; Kmax-P = 0.38 and 0.17 D; TCT = 19.64 and 11.19 µm) than that of the severe stage (K1 = 1.09 and 0.88 D; K2 = 1.41 and 0.87 D; Kmax-A = 2.74 and 2.15 D; Kmax-P = 0.82 and 0.22 D; TCT = 28.68 and 14.83 µm). These results show that the greater the keratoconus severity, the greater the change that must occur for it to be considered real. PB MDPI SN 2075-1729 YR 2023 FD 2023 LK https://uvadoc.uva.es/handle/10324/66490 UL https://uvadoc.uva.es/handle/10324/66490 LA eng NO Life, 2023, Vol. 13, Nº. 7, 1474 NO Producción Científica DS UVaDOC RD 27-dic-2024