RT info:eu-repo/semantics/article T1 Uncaria tomentosa-loaded chitosan oligomers–hydroxyapatite–carbon nitride nanocarriers for postharvest fruit protection A1 Santiago Aliste, Alberto A1 Sánchez Hernández, Eva A1 Buzón Durán, Laura A1 Marcos Robles, José Luis A1 Martín Gil, Jesús A1 Martín Ramos, Pablo K1 Agronomy K1 Biomaterials K1 Polymers K1 Polímeros K1 Nanotechnology K1 Nanotecnología K1 Chitosan K1 Microencapsulation K1 Food - Packaging K1 Alimentos - Envasado K1 Fungicides K1 Fruit - Postharvest diseases and injuries K1 Frutas - Enfermedades y plagas K1 Sustainable agriculture K1 Agricultura sostenible K1 Plants, Protection of K1 Cat’s claw K1 Garra de gato K1 3103 Agronomía K1 3102 Ingeniería Agrícola K1 3101.05 Fungicidas AB Given the risks associated with synthetic fungicides, it is crucial to explore safe and sustainable alternatives. One potential solution is using bioactive natural products (BNPs). However, BNPs face challenges like lability, solubility, and lack of specificity. These issues can be addressed through nanoencapsulation. This study focuses on the evaluation of novel chitosan oligomers–hydroxyapatite–carbon nitride (COS–HAp–g-C3N4) nanocarriers (NCs) for encapsulating BNPs, specifically an extract from Uncaria tomentosa bark. The NCs were characterized by transmission electron microscopy, energy-dispersive X-ray spectroscopy, and infrared spectroscopy. The NCs were monodisperse, with a mean diameter of 250 nm, and showed an encapsulation efficiency of 82%. The suitability of the loaded NCs (COS–HAp–g-C3N4–BNP, in a 2:1:0.5:1 weight ratio) for postharvest fruit protection was investigated in vitro and ex situ at a laboratory scale. Results regarding their efficacy against Botrytis cinerea on strawberries, Colletotrichum gloeosporioides on mangoes, Penicillium expansum on apples, Monilinia laxa on peaches, and Sclerotinia sclerotiorum on kiwifruit are presented. Minimum inhibitory concentrations of 250, 375, 375, 250, and 187.5 μg·mL−1 were found in vitro, respectively, while higher doses (500, 750, 750, 250, and 375 μg·mL−1, respectively) were needed to achieve effective control in postharvest tests on artificially inoculated fruit. These findings suggest that NCs containing extracts from U. tomentosa bark show promise as biorational agents and as alternatives to conventional fungicides for managing postharvest phytopathogens. PB MDPI SN 2073-4395 YR 2023 FD 2023 LK https://uvadoc.uva.es/handle/10324/66619 UL https://uvadoc.uva.es/handle/10324/66619 LA eng NO Agronomy, 2023, Vol. 13, Nº. 9, 2189 NO Producción Científica DS UVaDOC RD 26-dic-2024