RT info:eu-repo/semantics/article
T1 [3H]Spiroperidol binding in normal and denervated carotid bodies
A1 Dinger, Bruce
A1 González, Constancio
A1 Yoshizaki, Katsuaki
A1 Fidone, Salvatore
K1 Cuerpo carótido
AB Specific dopamine receptors were studied in freshly dissected, unhomogenized rabbit carotid bodiesincubated in [3H]spiroperidol. Total binding and non-specific binding were determined in the absenceand presence of 0.2 #M (+)-butaclamol, respectively. Specific binding in normal carotid bodiesincubated at near saturating concentrations (0.38 nM) was 1.63 _+ 0.58 pmol/g of tissue. Chronic sectionof the carotid sinus nerve (14 days) resulted in a 64070 reduction (P < 0.05) in specific binding. Weconclude that the majority of specific dopaminergic receptors are located on carotid sinus nerve afferentterminals.
PB Elsevier
SN 0304-3940
YR 1981
FD 1981
LK http://uvadoc.uva.es/handle/10324/6719
UL http://uvadoc.uva.es/handle/10324/6719
LA eng
NO Neuroscience Letters, 1981, 21, p. 51-55
NO Producción Científica
DS UVaDOC
RD 27-nov-2024