RT info:eu-repo/semantics/article
T1 Nutritional and lifestyle features in a Mediterranean cohort: An epidemiological instrument for categorizing metabotypes based on a computational algorithm
A1 García Perea, Aquilino
A1 Fernández Cruz, Edwin
A1 de la O Pascual, Victor
A1 Gonzalez Zorzano, Eduardo
A1 Moreno Aliaga, María J.
A1 Tur, Josep A.
A1 Martínez Hernández, José Alfredo
K1 Metabotype
K1 Lifestyles
K1 Calidad de vida
K1 Health
K1 Salud
K1 Public health
K1 Public health - Spain
K1 Salud pública - España
K1 Nutrition
K1 Mediterranean diet
K1 Alimentación - España
K1 Computer networks
K1 Redes de ordenadores
K1 Machine learning
K1 Aprendizaje automático
K1 32 Ciencias Médicas
K1 3212 Salud Publica
K1 3206 Ciencias de la Nutrición
K1 1203.17 Informática
AB Background and Objectives: Modern classification and categorization of individuals’ health requires personalized variables such as nutrition, physical activity, lifestyle, and medical data through advanced analysis and clustering methods involving machine learning tools. The objective of this project was to categorize Mediterranean dwellers’ health factors and design metabotypes to provide personalized well-being in order to develop professional implementation tools in addition to characterizing nutritional and lifestyle features in such populations. Materials and Methods: A two-phase observational study was conducted by the Pharmacists Council to identify Spanish nutritional and lifestyle characteristics. Adults over 18 years of age completed questionnaires on general lifestyle habits, dietary patterns (FFQ, MEDAS-17 p), physical activity (IPAQ), quality of life (SF-12), and validated well-being indices (LS7, MEDLIFE, HHS, MHL). Subsequently, exploratory factor, clustering, and random forest analysis methods were conducted to objectively define the metabotypes considering population determinants. Results: A total of 46.4% of the sample (n = 5496) had moderate-to-high adherence to the Mediterranean diet (>8 points), while 71% of the participants declared that they had moderate physical activity. Almost half of the volunteers had a good self-perception of health (49.9%). Regarding lifestyle index, population LS7 showed a fair cardiovascular health status (7.9 ± 1.7), as well as moderate quality of life by MEDLIFE (9.3 ± 2.6) and MHL scores (2.4 ± 0.8). In addition, five metabotype models were developed based on 26 variables: Westernized Millennial (28.6%), healthy (25.1%), active Mediterranean (16.5%), dysmetabolic/pre-morbid (11.5%), and metabolically vulnerable/pro-morbid (18.3%). Conclusions: The support of tools related to precision nutrition and lifestyle integrates well-being characteristics and contributes to reducing the impact of unhealthy lifestyle habits with practical implications for primary care. Combining lifestyle, metabolic, and quality of life traits will facilitate personalized precision interventions and the implementation of targeted public health policies.
PB MDPI
SN 1648-9144
YR 2024
FD 2024
LK https://uvadoc.uva.es/handle/10324/67382
UL https://uvadoc.uva.es/handle/10324/67382
LA eng
NO Medicina, 2024, Vol. 60, Nº. 4, 610
NO Producción Científica
DS UVaDOC
RD 11-jul-2024