RT info:eu-repo/semantics/article
T1 Antifungal activity of ribosome-inactivating proteins
A1 Iglesias Álvarez, María del Rosario
A1 Citores González, Lucía
A1 Gay, Claudia C.
A1 Ferreras Rodríguez, José Miguel
K1 Antifungal activity
K1 Transgenic plants
K1 Plantas transgénicas
K1 Plantas - Biotecnología
K1 Plant biotechnology
K1 Toxicology
K1 Fungal diseases of plants
K1 Plantas - Enfermedades y plagas
K1 Phytopathogenic fungi
K1 Hongos patógenos
K1 Ribosome inactivating protein
K1 Ribosomes
K1 Proteins - Synthesis
K1 Proteínas - Síntesis
K1 Analytical chemistry
K1 Biochemistry
K1 3214 Toxicología
K1 2302.27 Proteínas
K1 2301 Química Analítica
K1 2302 Bioquímica
AB The control of crop diseases caused by fungi remains a major problem and there is a need to find effective fungicides that are environmentally friendly. Plants are an excellent source for this purpose because they have developed defense mechanisms to cope with fungal infections. Among the plant proteins that play a role in defense are ribosome-inactivating proteins (RIPs), enzymes obtained mainly from angiosperms that, in addition to inactivating ribosomes, have been studied as antiviral, fungicidal, and insecticidal proteins. In this review, we summarize and discuss the potential use of RIPs (and other proteins with similar activity) as antifungal agents, with special emphasis on RIP/fungus specificity, possible mechanisms of antifungal action, and the use of RIP genes to obtain fungus-resistant transgenic plants. It also highlights the fact that these proteins also have antiviral and insecticidal activity, which makes them very versatile tools for crop protection.
PB MDPI
SN 2072-6651
YR 2024
FD 2024
LK https://uvadoc.uva.es/handle/10324/67432
UL https://uvadoc.uva.es/handle/10324/67432
LA eng
NO Toxins, 2024, Vol. 16, Nº. 4, 192
NO Producción Científica
DS UVaDOC
RD 12-jul-2024